1.08219

Tris(hydroxymethyl)aminomethane hydrochloride

EMPROVE^® EXPERT

• Szinonimák: Trizma^® hydrochloride, TRIS HCl, TRIS hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, Tromethane hydrochloride
• Lineáris képlet: NH₂C(CH₂OH)₃ · HCl
• CAS-szám: 1185-53-1
• Molekulatömeg: 157.60
• Beilstein: 3675235
• MDL-szám: MFCD00012590
• UNSPSC kód: 12352107
• EC index szám: 214-684-5

Tulajdonságok

• gőznyomás: <1 Pa ( 50 °C)
• Minőségi szint: 500
• termékcsalád: EMPROVE^® EXPERT
• Forma: solid
• Jellemzők: RNase and DNase free
• pH: 4.2 (20 °C, 100 g/L in H₂O)
• hasznos pH-tartomány: 7.0-9.0
• pKa (25 °C): 8.1
• mp: 150.7 °C
• oldhatóság: soluble 561 g/L
• sűrűség: 1.28 g/cm³ at 20.2 °C
• alkalmazás(ok): parenterals
• tárolási hőmérséklet: 15-25°C
• SMILES string: Cl.NC(CO)(CO)CO
• InChI: 1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H
• Nemzetközi kémiai azonosító kulcs: QKNYBSVHEMOAJP-UHFFFAOYSA-N

Leírás

Általános leírás

Finding the right chemical that matches your pharma and biopharma manufacturing needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for pharma and biopharma manufacturing withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Our SAFC^® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Egyéb megjegyzések

Due to its low microbial and endotoxin limits, Tris(hydroxymethyl)aminomethane hydrochloride Emprove^® Expert is suitable for biopharma manufacturing needs.

The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Jogi információk

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable