H-101

trans-3′-Hydroxycotinine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Tapasztalati képlet (Hill-képlet): C₁₀H₁₂N₂O₂
• CAS-szám: 34834-67-8
• Molekulatömeg: 192.21
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material
• Minőségi szint: 300
• form: liquid
• Jellemzők: (Snap-N-Spike^®)
• kiszerelés: ampule of 1 mL
• gyártó/kereskedő neve: Cerilliant^®
• koncentráció: 1.0 mg/mL in methanol
• technika/technikák: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• alkalmazás(ok): forensics and toxicology
• format: single component solution
• tárolási hőmérséklet: −20°C
• SMILES string: CN1[C@H](C2=CN=CC=C2)C[C@@H](O)C1=O
• InChI: 1S/C10H12N2O2/c1-12-8(5-9(13)10(12)14)7-3-2-4-11-6-7/h2-4,6,8-9,13H,5H2,1H3/t8-,9+/m0/s1
• Nemzetközi kémiai azonosító kulcs: XOKCJXZZNAUIQN-DTWKUNHWSA-N

Leírás

Általános leírás

Trans-3′-Hydroxycotinine is a major nicotine metabolite excreted in the urine of smokers and users of other tobacco or nicotine products including cigars, chewing tobacco and snuff. This Certified Spiking Solution^® is suitable for use in nicotine testing methods or clinical and diagnostic testing of nicotine biomarkers by LC-MS/MS or GC/MS.

Alkalmazás

• Wastewater-Based Tobacco Use Estimates: trans-3′-Hydroxycotinine is used as WBE biomarkers to to estimate tobacco use. It has significantly improved wastewater-based tobacco use estimates. This application enhances our understanding of public health trends by providing more accurate measurements of tobacco consumption in populations, using advanced environmental monitoring techniques (Zheng et al., 2023).


• Predicting Nicotine Metabolism: Trans-3′-Hydroxycotinine is utilized in genomic studies to predict nicotine metabolism across different ancestries, which helps in tailoring smoking cessation therapies based on individual genetic profiles.(Baurley et al., 2022).

Jogi információk

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Piktogramok: GHS02,GHS06,GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H225,H301 + H311 + H331,H370
• Óvintézkedésre vonatkozó mondatok: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Veszélyességi osztályok: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Célzott szervek: Eyes
• Tárolási osztály kódja: 3 - Flammable liquids
• WGK: WGK 1
• Lobbanási pont (F): 49.5 °F
• Lobbanási pont (C): 9.7 °C