QBD10503

Azido-dPEG^®₈-NHS ester

• Szinonimák: 2,5-Dioxo-1-pyrrolidinyl 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]propanoate, Polyethylene glycol
• Tapasztalati képlet (Hill-képlet): C₂₃H₄₀N₄O₁₂
• CAS-szám: 1204834-00-3
• Molekulatömeg: 564.58
• MDL-szám: MFCD13184949
• UNSPSC kód: 12161502
• PubChem Substance ID: 329823932
• NACRES: NA.22

Tulajdonságok

• Teszt: >90%
• Forma: solid or viscous liquid
• reakcióalkalmasság: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• funkcionális csoport: NHS ester; azide
• polimer felépítés: shape: linear; functionality: heterobifunctional
• kiszállítva: ambient
• tárolási hőmérséklet: −20°C
• SMILES string: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Leírás

Tulajdonságok és előnyök

The azido-dPEG^®₈-NHS ester contains an azide function on one end of a single molecular weight dPEG^® spacer(32.2 Å) and a reactive group (NHS ester) on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. N-hydroxysuccinimide (NHS) ester readily react with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

Jogi információk

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable