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719897

Sigma-Aldrich

Resomer® RG 502 H, Poly(D,L-lactide-co-glycolide)

acid terminated, viscosity 0.16-0.24 dL/g 

Szinonimák:

PLGA

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

Lineáris képlet:
[C3H4O2]x[C2H2O2]y
CAS-szám:
26780-50-7
UNSPSC kód:
12162002
NACRES:
NA.23

Minőségi szint

200

form

amorphous

adagolási arány

lactide:glycolide 50:50

lebomlási időtartam

<3 months

viszkozitás

0.16-0.24 dL/g

átmeneti hőmérséklet

Tg 42-46 °C

tárolási hőmérséklet

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

Nemzetközi kémiai azonosító kulcs

LCSKNASZPVZHEG-UHFFFAOYSA-N

Alkalmazás

Poly(D,L-lactide-co-glycolide) (PLGA) canbe used:

  • In the formulation ofa non-aqueous drug delivery system for H2S donors to aid thesustained release of the drug.
  • To prepare a polymer blend containing Ganciclovir-loaded microspheresdispersed in PLGA–PEG–PLGA polymer gel. This formulation can be used as asustained delivery system for Ganciclovir drug.
It can also be used to fabricate NO-releasingglucose and lactate sensors.

Jogi információk

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

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Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number
MKCV8978
BCCH1660
BCCG6651
BCCH6507
BCCG1383

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COA keresése

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Dokumentumtár megtekintése

Qinyi Yan et al.
Biosensors & bioelectronics, 26(11), 4276-4282 (2011-05-20)
Intravenous amperometric needle-type enzymatic glucose/lactate sensors intended for continuous monitoring are prepared with a novel nitric oxide (NO) releasing layer to improve device hemocompatibility. To create an underlying NO release coating, the sensors with immobilized enzymes (either glucose oxidase or
Diazeniumdiolate-doped poly (lactic-co-glycolic acid)-based nitric oxide releasing films as antibiofilm coatings.
Cai W,et al.
Biomaterials, 33(32), 7933-7944 (2012)
Sridhar Duvvuri et al.
Journal of controlled release : official journal of the Controlled Release Society, 108(2-3), 282-293 (2005-10-19)
The purpose of this work is to develop empirical equations for describing the in vitro ganciclovir (GCV) release from PLGA microspheres and also to develop and characterize a formulation containing GCV loaded PLGA microspheres dispersed in thermogelling PLGA-PEG-PLGA polymer gel.
A Patil et al.
AAPS PharmSciTech, 18(6), 2291-2302 (2017-01-20)
Hydrogen sulfide (H2S) targets both underlying factors in glaucoma pathogenesis by reducing elevated intraocular pressure (IOP) and providing retinal neuroprotection, whereas the current clinical approaches targets only reducing IOP. Therefore, H2S could be a potential superior candidate for glaucoma pharmacotherapy.
Z Zhuang et al.
Journal of dental research, 98(2), 200-208 (2018-11-06)
Periodontitis is characterized by the progressive destruction of tooth-supporting alveolar bone, which is mainly caused by chronic inflammation in response to persistent bacterial insult. It has recently become clear that the pathogenesis of periodontitis is associated with a high ratio
View All Related Papers

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Összes mutatása

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