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719889

Sigma-Aldrich

Resomer® RG 502, Poly(D,L-Lactide-co-Glycolide)

lactide:glycolide 50:50, ester terminated, Mw 7,000-17,000

Szinonimák:

PLGA

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
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About This Item

Lineáris képlet:
[C3H4O2]x[C2H2O2]y
UNSPSC kód:
12162002
NACRES:
NA.23

Minőségi szint

200

form

amorphous

adagolási arány

lactide:glycolide 50:50

molekulatömeg

Mw 7,000-17,000

lebomlási időtartam

<3 months

viszkozitás

0.16-0.24 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

átmeneti hőmérséklet

Tg 42-46 °C

kiszállítva

wet ice

tárolási hőmérséklet

2-8°C

Alkalmazás

Resomer® RG 502 can be used to formulate a PLGA-based nano drug delivery system for the anti-inflammatory drug, 6-bromoindirubin-3′-glycerol-oxime ether (6BIGOE).

Itcan also be used to prepare control release formulations for Naloxone HCldelivery.

Tulajdonságok és előnyök

  • Biocompatible
  • Biodegradable
  • Can be processed into almost any shape and size
  • Tunable mechanical properties

Jogi információk

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number
MKCW1516
BCCF8231
BCCG8280
BCCF0447
BCCD0959

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COA keresése

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Dokumentumtár megtekintése

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Kyle E Broaders et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(14), 5497-5502 (2009-03-27)
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Biomaterials, 34(9), 2213-2220 (2013-01-08)
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Cikkek

RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Poly(Glycerol Sebacate) in Tissue Engineering

Synthetic aliphatic polyesters dominate resorbable biomaterials in clinical use.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

Therapeutic Nanoparticles Harness Myeloid Cells for Brain Tumor-Targeted Delivery and Immunomodulation

Immunosuppressive tumor-associated myeloid cells (TAMC) are responsible for glioblastoma (GBM) resistance to immunotherapies and existing standard of care treatments. This mini-review highlights recent progress in implementing nanotechnology in advancing TAMC-targeted therapies for GBM.

Összes mutatása

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

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