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Merck

48700

Sigma-Aldrich

Octyl gallate

antioxidant, ≥99.0% (HPLC)

Szinonimák:

Octyl 3,4,5-trihydroxybenzoate, n-Octyl gallate

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Lineáris képlet:
3,4,5-(HO)3C6H2CO2(CH2)7CH3
CAS-szám:
Molekulatömeg:
282.33
Beilstein:
2132305
EC-szám:
MDL-szám:
UNSPSC kód:
12352100
PubChem Substance ID:
NACRES:
NA.22

Minőségi szint

Teszt

≥99.0% (HPLC)

mp

101-103 °C
101-104 °C (lit.)

oldhatóság

soluble 2.5%, clear, colorless (AcOH (MEOH))

funkcionális csoport

ester

SMILES string

CCCCCCCCOC(=O)c1cc(O)c(O)c(O)c1

InChI

1S/C15H22O5/c1-2-3-4-5-6-7-8-20-15(19)11-9-12(16)14(18)13(17)10-11/h9-10,16-18H,2-8H2,1H3

Nemzetközi kémiai azonosító kulcs

NRPKURNSADTHLJ-UHFFFAOYSA-N

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Általános leírás

Octyl gallate (3,4,5-trihydroxybenzoate) is reported to possess antifungal activity against Saccharomyces cerevisiae and Zygosaccharomyces bailii. The fungicidal activity associated with octyl gallate is due to its ability to act as a nonionic surface-active agent (surfactant). Octyl gallate, an alkyl gallate, is reported to exhibit direct antibacterial activity against Staphylococcus aureus BB568. It is reported to inhibit the activity of soybean lipoxygenase-1 (EC 1.13.11.12, type I) with an IC50 of 1.3μM. It is also effective in preventing lipid peroxidation.

Alkalmazás

Octyl gallate was used in a study to investigate the self-assembly in two comb-shaped supramolecules systems consisting of octyl gallate, hydrogen bonded to the pyridine groups of polyisoprene-block-poly(vinylpyridine) diblock copolymers using synchrotron radiation.

Jogi nyilatkozat

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Piktogramok

Exclamation mark

Figyelmeztetés

Warning

Figyelmeztető mondatok

Óvintézkedésre vonatkozó mondatok

Veszélyességi osztályok

Acute Tox. 4 Oral - Skin Sens. 1

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 1

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Analitikai tanúsítványok (COA)

Lot/Batch Number

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Dokumentumtár megtekintése

Self-Assembly of Supramolecules Consisting of Octyl Gallate Hydrogen Bonded to Polyisoprene-b lock-poly (vinylpyridine) Diblock Copolymers.
Bondzic S, et al.
Macromolecules, 37(25), 9517-9524 (2004)
Xiaojun Li et al.
Drug metabolism and pharmacokinetics, 26(4), 341-350 (2011-03-23)
Ferulic acid (FA), a member of the hydroxycinnamate family, is an abundant dietary antioxidant that may offer beneficial effects against cancer, cardiovascular disease, diabetes, osteoarthritis and Alzheimer's disease. In this study, evidence for sulfation and glucuronidation of FA was investigated
Tsutomu Arakawa et al.
International journal of pharmaceutics, 355(1-2), 220-223 (2008-02-05)
Arginine suppresses protein-protein and protein-surface interactions and thus is expected to increase the solubility of the proteins. We have examined here the effects of arginine on the solubility of a highly insoluble protein, gluten, and two organic compounds, octyl-gallate and
I Kubo et al.
Bioorganic & medicinal chemistry letters, 11(3), 347-350 (2001-02-24)
Octyl gallate (3,4,5-trihydroxybenzoate) was found to possess antifungal activity against Saccharomyces cerevisiae and Zygosaccharomyces bailii, in addition to its potent antioxidant activity. Catechol moiety is essential to elicit this activity. The primary fungicidal activity of octyl gallate comes from its
Javier Rúa et al.
Foodborne pathogens and disease, 8(1), 149-157 (2010-11-03)
Six pure phenolic compounds (hydroquinone, thymol, carvacrol, butylated hydroxyanisole, gallic acid, and octyl gallate) were tested for their minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against several strains of Staphylococcus aureus isolated from dairy and meat products. In

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