Key Documents

Propranolol hydrochloride

Name: Propranolol hydrochloride
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

(±)-Propranolol hydrochloride, (±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride, DL-Propranolol hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₂₁NO₂ · HCl

CAS Number:

318-98-9

Molecular Weight:

295.80

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750990

MDL number:

MFCD00012558

Beilstein/REAXYS Number:

4164259

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Properties

grade

pharmaceutical primary standard

API family

propranolol

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.CC(C)NCC(O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChI key

ZMRUPTIKESYGQW-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153), ADRB2(154)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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This Item	BP1196	PHR1308	Y0002135
USP 1576005 Propranolol hydrochloride	BP1196 Propranolol hydrochloride	Supelco PHR1308 Propranolol hydrochloride	Y0002135 Propranolol for system suitability
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade -
manufacturer/tradename USP	manufacturer/tradename BP	manufacturer/tradename -	manufacturer/tradename EDQM
format neat	format neat	format neat	format -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical
Gene Information human ... ADRB1(153), ADRB2(154)	Gene Information human ... ADRB1(153), ADRB2(154)	Gene Information human ... ADRB1(153), ADRB2(154)	Gene Information human ... ADRB1(153), ADRB2(154)
API family propranolol	API family propranolol	API family propranolol	API family propranolol

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pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

pcodes

P264 - P270 - P301 + P312 - P501

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Treatment of a tongue lymphangioma with sirolimus after failure of surgical resection and propranolol.

Canan Akyüz et al.

Pediatric blood & cancer, 61(5), 931-932 (2013-11-23)

Lymphangiomas of the tongue are rare, and their treatment is problematic. A 10 year-old patient with tongue lymphangioma who was previously treated with surgery and propranolol with no response was treated with sirolimus in our department. We used sirolimus with

Diagnosis and management of infantile hemangiomas.

Katherine B Püttgen

Pediatric clinics of North America, 61(2), 383-402 (2014-03-19)

Propranolol has replaced corticosteroids as preferred first-line therapy for the management of infantile hemangiomas (IH). The topical β-blocker timolol is now an alternative to oral propranolol and watchful waiting for smaller IH. Research in the last decade has provided evidence-based

Activation of hepatic inflammatory pathways by catecholamines is associated with hepatic insulin resistance in male ischemic stroke rats.

Ya-Yu Wang et al.

Endocrinology, 155(4), 1235-1246 (2014-01-21)

Patients who experience acute ischemic stroke may develop hyperglycemia, even in the absence of diabetes. In the current study we determined the effects of acute stroke on hepatic insulin signaling, TNF-α expression, endoplasmic reticulum (ER) stress, the activities of c-Jun

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Global Trade Item Number

SKU	GTIN
1576005-200MG	04061838743435