Key Documents

View All Documentation

D,L-Sulforaphane

Name: D,L-Sulforaphane
Brand: SIGMA

≥90% (HPLC), liquid, phase II detoxification enzymes inducer

Synonym(s):

1-Isothiocyanato-4-(methylsulfinyl)-butane

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₆H₁₁NOS₂

CAS Number:

4478-93-7

Molecular Weight:

177.29

UNSPSC Code:

12352200

PubChem Substance ID:

24724610

NACRES:

NA.77

MDL number:

MFCD00198068

Assay:

≥90% (HPLC)

Form:

liquid

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

DL-Sulforaphane, ≥90% (HPLC), synthetic, liquid

biological source

synthetic

Quality Segment

200

assay

≥90% (HPLC)

form

liquid

solubility

DMSO: soluble 40 mg/mL, H₂O: insoluble

compatibility

for use with ABI 7500

shipped in

dry ice

storage temp.

−20°C

SMILES string

CS(=O)CCCCN=C=S

InChI

1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3

InChI key

SUVMJBTUFCVSAD-UHFFFAOYSA-N

Description

Application

LNCaP prostate cancer cells were treated with DL-Sulforaphane to study the effect on androgen receptor.[1] Effects on malathion toxicity was studied in rats by treating them with DL-Sulforaphane.[2]

Biochem/physiol Actions

Selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Organosulfur compound found in cruciferous vegetables, including broccoli.

Sulforaphane is an anti-cancer, anti-microbial and anti-diabetic compound found in cruciferous vegetables.[3][4] It induces the production of detoxifying enzymes such as quinone reductase and glutathione S-transferase that cause xenobiotic transformation. Sulforaphane also increases the transcription of tumor suppressor proteins and inhibits histone deacetylases. It modulates inflammatory responses by suppressing the LPS-mediated expression of iNOS, COX-2, IL-1β and TNF-α.[3][5]

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	S6317	574215	L2540
Sigma-Aldrich S4441 DL-Sulforaphane	Sigma-Aldrich S6317 L-Sulforaphane	Sigma-Aldrich 574215 D,L-Sulforaphane	Sigma-Aldrich L2540 L-368,899
form liquid	form oil	form liquid	form powder
assay ≥90% (HPLC)	assay ≥95% (HPLC)	assay ≥98% (UPLC)	assay ≥98% (HPLC)
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
solubility DMSO: soluble 40 mg/mL, H₂O: insoluble	solubility DMSO: >5 mg/mL	solubility ethanol: 10 mg/mL, DMSO: 20 mg/mL	solubility H₂O: soluble 20 mg/mL
shipped in dry ice	shipped in -	shipped in ambient	shipped in -

Still not finding the right product?

Explore all of our products under DL-Sulforaphane

Storage Class

10 - Combustible liquids

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.