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Serum Replacement 1 (50×)

Name: Serum Replacement 1 (50×)
Brand: SIGMA

liquid, sterile-filtered, suitable for cell culture

Synonym(s):

50× Serum Replacement, Cell Culture Serum Substitute, Replacement Serum

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About This Item

NACRES:

NA.71

UNSPSC Code:

12352207

Sterility:

sterile-filtered

Form:

liquid

Pricing and availability is not currently available.

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Properties

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

storage temp.

2-8°C

Description

Application

Serum Replacement 1 (50×) has been used as a supplement in Ham′s/F-12 medium for tumour cells. It has also been used as a supplement to culture Jurkat T cells in RPMI medium.(2)

Other Notes

Defined, multi-purpose serum replacement useful in studying the effects of growth factors and the production of proteins. Contains highly purified, heat-treated bovine serum albumin, heat-treated bovine transferrin and bovine insulin. Does not contain growth factors, steroid hormones, glucocorticoids, cell adhesion factors, detectable Ig and mitogens. May be used with anchorage-dependent and suspension cells.

Disclaimer

Stable for 30 days when diluted in cell culture medium.

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Show Differences

1 of 1

This Item	S9388	S2640	O3008
Sigma-Aldrich S0638 Serum Replacement 1 (50×)	Sigma-Aldrich S9388 Serum Replacement 2 (50×)	Sigma-Aldrich S2640 Serum Replacement 3 (50×)	Sigma-Aldrich O3008 Oleic Acid-Albumin from bovine serum
sterility sterile-filtered	sterility sterile-filtered	sterility sterile-filtered	sterility sterile-filtered
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
form liquid	form liquid	form liquid	form liquid
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
impurities endotoxin, tested	impurities endotoxin, tested	impurities endotoxin, tested	impurities endotoxin, tested
BSA/insulin/transferin containing	serum-booster, high serum requiring cells	enhance protein secretion, enhance protein expression levels	solubilized oleic acid, oleic acid cell delivery form, in vitro use

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Proliferation and intracellular glutathione in Jurkat T cells with concentrated whey protein products

Middleton N, et al.

International Journal of Dairy Technology, 13(7), 565-573 (2003)

Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function.

Constanze M Hammerle et al.

PLoS genetics, 16(10), e1009069-e1009069 (2020-10-16)

The genetic mechanisms that determine the size of the adult pancreas are poorly understood. Imprinted genes, which are expressed in a parent-of-origin-specific manner, are known to have important roles in development, growth and metabolism. However, our knowledge regarding their roles

Global Trade Item Number

SKU	GTIN
S0638-100ML	04061836830434
S0638-10ML	04061836830458

Questions

Anonymous

2 years ago

What is the difference between Serum Replacement 1, 2, and 3?

1 answer
1. Technical Support
  
  2 years ago
  
  These concentrated serum replacements are defined, as multipurpose products designed to eliminate the need for serum in culture. These products do not contain growth factors, steroid hormones, or mitogens.
  
  S0638 Serum Replacement 1, 50X
  Total protein concentration at 1X of 770 mg/mL
  Highly purified bovine serum albumin (heat treated)
  Bovine transferrin (heat treated)
  Bovine insulin
  
  S9388 Serum Replacement 2, 50X
  Total protein concentration at 1X of 570 mg/mL
  Highly purified bovine serum albumin (heat treated)
  Bovine transferrin (heat treated)
  Bovine insulin
  
  S2640 Serum Replacement 3, 50X
  Total protein concentration at 1X of 664 mg/mL
  Highly purified human serum albumin (heat treated)
  Human transferrin (heat treated)
  Human (recombinant) insulin
  
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