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L8045
Liquiritin
from Glycyrrhizae root (licorice root), ≥98% (HPLC)
Synonym(s):
4′,7-Dihydroxyflavanone 4′-glucoside, Liquiritoside
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About This Item
Empirical Formula (Hill Notation):
C21H22O9
CAS Number:
Molecular Weight:
418.39
UNSPSC Code:
12352200
NACRES:
NA.25
MDL number:
Pricing and availability is not currently available.
biological source
Glycyrrhizae root (licorice root)
Quality Segment
assay
≥98% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
O=C1C2=CC=C(O)C=C2O[C@H](C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3)C1
InChI
1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1
InChI key
DEMKZLAVQYISIA-ZRWXNEIDSA-N
General description
Application
Liquiritin has been used to analyze the extract of Glycyrrhiza uralensis and examine its components for anti-Hepatitis C virus activity.[1]
Biochem/physiol Actions
Liquiritin has been attributed to show antidepressant-like and antioxidant activity.[4] It causes apoptosis in cell lines having gastric cancer and promyelocytic leukemia. Liquiritin also demonstrates neurotrophic effects and hence has been considered as a potential contender for the management of different neurodegenerative diseases.[2] It shows an anti-inflammatory property with protection to the liver against oxidative damage.[3] It has depigmenting ability and is a potential medicine for melasma.[5]
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This Item | |||
|---|---|---|---|
| form powder | form powder or crystals | form - | form solid |
| biological source Glycyrrhizae root (licorice root) | biological source - | biological source - | biological source - |
| assay ≥98% (HPLC) | assay ≥97.0% (HPLC) | assay ≥90.0% (HPLC) | assay ≥85.0% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level - |
| application(s) metabolomics | application(s) metabolomics | application(s) food and beverages | application(s) - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Zhiyu Zhao et al.
Behavioural brain research, 194(1), 108-113 (2008-07-29)
Many flavonoids extracted from nature plants have been reported to exert antidepressant-like effect in animal studies. The present study was designed to observe the effects of liquiritin, a flavone compound derived from Glycyrrhiza uralensis, on the behaviors of chronic variable
Zheng-Ai Chen et al.
Cytotechnology, 60(1-3), 125-132 (2009-10-01)
Neurite outgrowth and neuronal differentiation play a crucial role in the development of the nervous system. Understanding of neurotrophins induced neurite outgrowth was important to develop therapeutic strategy for axon regeneration in neurodegenerative diseases as well as after various nerve
Qiuyan Guo et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 123, 109812-109812 (2020-01-17)
Wu-tou decoction (WTD), a classic Traditional Chinese medicine formula, has been extensively used in the treatment of neuropathic pain (NP) such as chronic inflammatory pain, trigeminal neuralgia, and cancer-induced pain. Our previous studies have shown that the severity of mechanical
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L8045-10MG | 04061833965887 |
| L8045-50MG | 04061833050682 |
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Which genus of licorice root is the Liquiritin from; G.glabra, G.inflata, or G.uralensis?
1 answer-
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