This item has not been tested for the use in cell culture applications. However, the product has been used successfully by other researchers in a number of publications. Please see the link below to review one example:
Human mesenchymal stromal cell-secreted lactate induces M2-macrophage differentiation by metabolic reprogramming.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5058674/
L6402
L-(+)-Lactic acid
BioXtra, ≥98% (titration)
Synonym(s):
(S)-2-Hydroxypropionic acid, Sarcolactic acid
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About This Item
Empirical Formula (Hill Notation):
C3H6O3
CAS Number:
Molecular Weight:
90.08
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
201-196-2
Beilstein/REAXYS Number:
1720251
MDL number:
Assay:
≥98% (titration)
Pricing and availability is not currently available.
product line
BioXtra
Quality Level
assay
≥98% (titration)
impurities
≤0.005% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.1%
solubility
H2O: 1 M at 20 °C, clear, colorless
anion traces
chloride (Cl-): ≤0.05%, sulfate (SO42-): ≤0.05%
cation traces
Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%
storage temp.
2-8°C
SMILES string
C[C@H](O)C(O)=O
InChI
1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
InChI key
JVTAAEKCZFNVCJ-REOHCLBHSA-N
Biochem/physiol Actions
L-(+)-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.
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This Item | |||
|---|---|---|---|
| assay ≥98% (titration) | assay - | assay 80% | assay ≥98% |
| Quality Level 200 | Quality Level 300 | Quality Level 100 | Quality Level 200 |
| solubility H2O: 1 M at 20 °C, clear, colorless | solubility - | solubility water: soluble(lit.) | solubility - |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. 2-8°C |
| cation traces Al: ≤0.0005%, Cu: ≤0.0005%, K: ≤0.005%, NH4+: ≤0.05%, Pb: ≤0.001%, Ca: ≤0.0005%, Mg: ≤0.0005%, Zn: ≤0.0005%, Fe: ≤0.0005%, Na: ≤0.005% | cation traces - | cation traces Ca: ≤100 mg/kg, Fe: ≤10 mg/kg | cation traces - |
| impurities ≤0.005% Phosphorus (P), ≤0.1% Insoluble matter | impurities - | impurities - | impurities - |
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1C
supp_hazards
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Silvia Selleri et al.
Oncotarget, 7(21), 30193-30210 (2016-04-14)
Human mesenchymal stromal cells (MSC) have been shown to dampen immune response and promote tissue repair, but the underlying mechanisms are still under investigation. Herein, we demonstrate that umbilical cord-derived MSC (UC-MSC) alter the phenotype and function of monocyte-derived dendritic
David M Garcia et al.
eLife, 5 (2016-12-03)
Robust preference for fermentative glucose metabolism has motivated domestication of the budding yeast Saccharomyces cerevisiae. This program can be circumvented by a protein-based genetic element, the [GAR+] prion, permitting simultaneous metabolism of glucose and other carbon sources. Diverse bacteria can
Koen Poesen et al.
Clinical chemistry and laboratory medicine, 51(7), 1417-1427 (2013-03-16)
With the use of a traditional blood gas analyzer (BGA) (ABL800 Radiometer) for blood glucose monitoring, tight glucose control (TGC) reduced in-hospital mortality and morbidity of surgical intensive care unit (ICU) adult and pediatric patients. Such BGAs are now superseded
Global Trade Item Number
| SKU | GTIN |
|---|---|
| L6402-5G | 04061833958803 |
| L6402-1G | 04061833958797 |
| L6402-10G | 04061833958780 |
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Can this product be used for cell culture (mammalian).
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Is this product sterile for biological use (for research)?
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This product is tagged as a BioXtra, which means it is intended for biological use, but it is not sterilized. It could be solubilized in sterile, ultrapure water. A sterilized solution such as product 63325 may be more suitable: https://www.sigmaaldrich.com/US/en/product/sial/63325
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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