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(−)-Epicatechin

Name: (−)-Epicatechin
Brand: SIGMA

≥98% (HPLC), from green tea

Synonym(s):

(−)-cis-3,3′,4′,5,7-Pentahydroxyflavane, (2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₄O₆

CAS Number:

490-46-0

Molecular Weight:

290.27

UNSPSC Code:

12352205

NACRES:

NA.77

PubChem Substance ID:

24894538

EC Number:

207-710-1

Beilstein/REAXYS Number:

92760

MDL number:

MFCD00075648

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Properties

biological source

green tea

Quality Level

200

assay

≥98% (HPLC)

mp

240 °C (dec.) (lit.)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1

InChI key

PFTAWBLQPZVEMU-UKRRQHHQSA-N

Gene Information

human ... BACE1(23621), CYP1A2(1544)

Description

General description

Epicatechin is a flavanol, that belongs to the class of secondary, polyphenolic plant metabolites.

Application

(-)-Epicatechin has been used:

to examine its biological effects in cell lines from human gender-specific cancers
to study its antiviral activity
to test its ability to regenerate this enzymatic activity both in vitro at the isolated MPO−H₂O₂−Cl- system and ex vivo in human polymorphonuclear leukocytes (PMNs)

Biochem/physiol Actions

This antioxidant is found in chocolate. (-)-Epicatechin is linked with cardiovascular effects. It is considered as a dependable standard due to its availability in cacao seeds and cocoa products. The halogenating activity of myeloperoxidase can be restored by (-)-epicatechin.

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1 of 1

This Item	E1753	68097	74873
Sigma-Aldrich E4018 (−)-Epicatechin	Sigma-Aldrich E1753 (−)-Epicatechin	Supelco 68097 (−)-Epicatechin	Supelco 74873 (−)-Epicatechin
biological source green tea	biological source -	biological source -	biological source -
assay ≥98% (HPLC)	assay ≥90% (HPLC)	assay ≥97.0% (HPLC)	assay -
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 300
application(s) metabolomics vitamins, nutraceuticals, and natural products	application(s) metabolomics vitamins, nutraceuticals, and natural products	application(s) food and beverages	application(s) food and beverages
storage temp. 2-8°C	storage temp. -	storage temp. 2-8°C	storage temp. 2-8°C
Gene Information human ... BACE1(23621), CYP1A2(1544)	Gene Information human ... BACE1(23621), CYP1A2(1544)	Gene Information -	Gene Information -

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Explore all of our products under (−)-Epicatechin

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Global Trade Item Number

SKU	GTIN
E4018-1MG	04061833603512
E4018-5MG	04061833603529

Questions

1–2 of 2 Questions

Anonymous

10 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  10 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
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