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Fluorescein isothiocyanate–dextran

Name: Fluorescein isothiocyanate–dextran
Brand: SIGMA

average mol wt 150,000, (FITC:Glucose = 1:160)

Synonym(s):

FITC-Dextran 150, FITC–Dextran

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About This Item

CAS Number:

60842-46-8

UNSPSC Code:

12352201

NACRES:

NA.32

MDL number:

MFCD00131092

Pricing and availability is not currently available.

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Properties

form

solid

Quality Segment

100

mol wt

average mol wt 150,000

composition

(FITC:Glucose = 1:160)

extent of labeling

~0.004 mol/mol FITC glucose

solubility

H₂O: 25 mg/mL, slightly hazy, very deep yellow-orange

fluorescence

λ_ex 492 nm; λ_em 518 nm in 0.1 M phosphate pH 8.0

storage temp.

2-8°C

Description

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Fluorescein isothiocyanate–dextran (FITC-Dextran 150) is use as a fluorescent probe to study cell permeability. FITC-Dextran 150 is useful to study processes that affect the permeability of the blood brain barrier (BBB) and microvascular structures. FITC-Dextran 150 is used in fluorescence microlymphography.

Other Notes

Commonly utilized as a macromolecular fluorochrome in inflammatory studies[1]

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1 of 1

This Item	46945	46944	FD10S
Sigma-Aldrich 46946 Fluorescein isothiocyanate–dextran	Sigma-Aldrich 46945 Fluorescein isothiocyanate–dextran	Sigma-Aldrich 46944 Fluorescein isothiocyanate–dextran	Sigma-Aldrich FD10S Fluorescein isothiocyanate–dextran
solubility H₂O: 25 mg/mL, slightly hazy, very deep yellow-orange	solubility H₂O: 50 mg/mL, hazy, orange to very deep orange	solubility H₂O: 50 mg/mL, slightly hazy, orange	solubility water: 25 mg/mL, cloudy to hazy, yellow to orange
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
form solid	form powder	form powder	form powder
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
extent of labeling ~0.004 mol/mol FITC glucose	extent of labeling ~0.004 mol/mol FITC glucose	extent of labeling ~0.004 mol/mol FITC glucose	extent of labeling 0.003-0.020 mol FITC per mol glucose
mol wt average mol wt 150,000	mol wt average mol wt 70,000	mol wt average mol wt 4,000	mol wt average mol wt 10,000

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pictograms

GHS07

signalword

Warning

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

hcodes

H315,H319,H335

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Global Trade Item Number

SKU	GTIN
46946-5G-F	04061833354070
46946-100MG-F	04061832358918
46946-500MG-F	04061832532189

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