54752
Methyl 4-hydroxybenzoate
tested according to Ph. Eur.
Synonym(s):
Methylis parahydroxybenzoas, p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN
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About This Item
Recommended Products
Agency
USP/NF
tested according to Ph. Eur.
Assay
99.7%
form
solid
mp
125-128 °C (lit.)
application(s)
pharmaceutical (small molecule)
SMILES string
COC(=O)c1ccc(O)cc1
InChI
1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
InChI key
LXCFILQKKLGQFO-UHFFFAOYSA-N
Gene Information
rat ... Ar(24208)
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Application
- Single crystal, Hirshfeld surface and theoretical analysis of methyl 4-hydroxybenzoate, a common cosmetic, drug and food preservative-Experiment versus theory.: This research provides a detailed analysis of the crystal structure of Methyl 4-hydroxybenzoate, offering insights into its stability and effectiveness as a preservative in various applications, including cosmetics and pharmaceuticals (Sharfalddin et al., 2020).
- Photostabilization of papaverine hydrochloride solutions.: This article explores the role of Methyl 4-hydroxybenzoate in enhancing the photostability of papaverine hydrochloride solutions, crucial for maintaining the efficacy of this pharmaceutical under exposure to light (Piotrowska et al., 2010).
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
334.4 °F
Flash Point(C)
168 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Methyl paraben (CAS No. 99-76-3) is a methyl ester of p-hydroxybenzoic acid. It is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics for over 50 years. Methyl paraben is readily and completely absorbed through
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