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L1012

Ácido linoleico

liquid, BioReagent, suitable for cell culture

Sinónimos:

Ácido cis-9,cis-12-octadecadienoico

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Acerca de este artículo

Fórmula lineal:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
Número CAS:
Peso molecular:
280.45
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
32190102
UNSPSC Code:
12352211
EC Number:
200-470-9
MDL number:
Beilstein/REAXYS Number:
1727101
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biological source

plant (Safflower oil)

Quality Segment

product line

BioReagent

assay

≥98%

form

liquid

technique(s)

cell culture | mammalian: suitable

refractive index

n20/D 1.466 (lit.)

bp

229-230 °C/16 mmHg (lit.)

mp

−5 °C (lit.)

solubility

NaOH: 1 M, ethanol: soluble

density

0.902 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

OC(CCCCCCC/C=C\C/C=C\CCCCC)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-

InChI key

OYHQOLUKZRVURQ-HZJYTTRNSA-N

Gene Information

General description

Linoleic acid (LA) is the precursor for the synthesis of arachidonic prostaglandins and other eicosanoids. LA is present in vegetable oils and meat.

Application

Fatty acid that is typically bound to a carrier molecule such as BSA or cyclodextrin for use in cell culture.
Linoleic acid has been used as a component of S12 medium for cardiomyocytes differentiation, minimum essential medium α for spermatogonial stem cell culture and for endothelial differentiation of mouse adipose-derived stem cells (mASC).

Biochem/physiol Actions

El ácido linoleico aumenta la proliferación celular y la expresión génica del receptor activado por proliferadores peroxisómicos tipo alfa, PPARα, y sus genes de interés, como el de la acil-CoA oxidasa en hepatocitos primarios de pato .
Linoleic acid (LA) may improve wound healing in diabetic rat. The levels of LA in adipose tissue and platelets are correlated with coronary artery disease. It may induce tumor and apoptosis in colorectal cancer cells. Studies also support their protective effects in lymphocytes. Linoleic acid is typically bound to a carrier molecule such as bovine serum albumin (BSA) or cyclodextrin for use in cell culture.

Packaging

Sealed ampule.

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Este artículo
62240L137662230
technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

assay

≥98%

assay

-

assay

≥98%

assay

≥98.0% (GC)

biological source

plant (Safflower oil)

biological source

-

biological source

plant oil (safflower)

biological source

-

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

2-8°C

form

liquid

form

liquid

form

liquid

form

-

solubility

NaOH: 1 M, ethanol: soluble

solubility

-

solubility

-

solubility

-


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Questions

1–2 of 2 Questions  
  1. What volume does the 100mg come dissolved in, i.e., what is the initial concentration? I have 50uL of liquid left, how can I figure out how many mg that is?

    1 answer
    1. Linoleic Acid is provided as a neat, pure liquid. The initial volume can be calculated by dividing the mass by the density. For example, a 100 mg bottle will contain 0.1g divided by 0.902 g/mL, which equals 110 µL.

      Helpful?

  2. What is the concentration (g/L) of the solution

    1 answer
    1. This product is a neat or pure liquid and has not been diluted. The material has a density of 0.902 g/mL and a minimum purity of 99%.

      Helpful?

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