This product is a ready-to-use 8 M guanidine hydrochloride solution buffered at pH 8.5 with 0.05 M bicine.
G7294
Guanidine hydrochloride solution
8 M, pH 8.5, buffered aqueous solution
Sinónimos:
Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, GuHCl, Guanidine HCl, Guanidinium chloride, Guanidium chloride
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NACRES:
NA.25
UNSPSC Code:
12352209
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Servicio técnico
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buffered aqueous solution
Quality Segment
concentration
8 M
color
colorless
pH
8.5
application(s)
diagnostic assay manufacturing
Application
Guanidine hydrochloride solution has been used:
- as a denaturing agent during the preparation of HEK293T cells and in the resuspension buffer to prevent protein aggregation during the homogenization process in mouse tissue preparation.
- for the extraction of total RNA from plant samples.
- for the digestion of plasma and HDL proteins.
- for the denaturation of proteins during the conformational stability assay of misfolded prion proteins.
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Este artículo | |||
|---|---|---|---|
| concentration 8 M | concentration ~8 M in H2O | concentration 6 M | concentration - |
| Quality Level 200 | Quality Level 100 | Quality Level 500 | Quality Level 200 |
| application(s) diagnostic assay manufacturing | application(s) advanced drug delivery | application(s) advanced drug delivery | application(s) - |
| form buffered aqueous solution | form liquid | form liquid | form liquid |
| pH 8.5 | pH 4.5-7.5 (25 °C) | pH 4.5—5.5 | pH - |
| color colorless | color - | color colorless | color - |
signalword
Warning
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Clase de almacenamiento
10 - Combustible liquids
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Can you please share the information on the buffer in which this guanidine hydrochloride solution is made? I want to understand the buffer is not interfering in my analysis. Is this sodium bicarbonate buffer or tris buffer?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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