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C3630

Creatine monohydrate

Name: Creatine monohydrate
Brand: SIGMA

≥98%, suitable for cell culture

Sinónimos:

Creatine hydrate, Creatine, monohydrate, N-(aminoiminomethyl)-N-methyl-glycine hydrate

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Fórmula empírica (notación de Hill):

C₄H₉N₃O₂ · H₂O

Número CAS:

6020-87-7

Peso molecular:

149.15

NACRES:

NA.26

PubChem Substance ID:

24892629

UNSPSC Code:

12352209

EC Number:

200-306-6

MDL number:

MFCD00071582

Beilstein/REAXYS Number:

7942755

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Propiedades

Nombre del producto

Creatine monohydrate, ≥98%

Quality Level

200

assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

mp

292 °C

SMILES string

O.CN(CC(O)=O)C(N)=N

InChI

1S/C4H9N3O2.H2O/c1-7(4(5)6)2-3(8)9;/h2H2,1H3,(H3,5,6)(H,8,9);1H2

InChI key

MEJYXFHCRXAUIL-UHFFFAOYSA-N

Descripción

Application

Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action.

Biochem/physiol Actions

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP.

Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

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Este artículo	P7936	8.41470	L9037
Sigma-Aldrich C3630 Creatine monohydrate	Sigma-Aldrich P7936 Phosphocreatine disodium salt hydrate	Sigma-Aldrich 8.41470 Creatine monohydrate	Sigma-Aldrich L9037 L-Lysine monohydrate
form powder	form powder	form powder	form crystalline powder
assay ≥98%	assay ≥97%	assay -	assay 98.5-101.5% dry basis
technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) -	technique(s) cell culture \| mammalian: suitable
color white to off-white	color white	color -	color white
mp 292 °C	mp -	mp 296-297 °C (decomposition)	mp 215 °C
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 300

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Abnormal creatine transport of mutations in monocarboxylate transporter 12 (MCT12) found in patients with age-related cataract can be partially rescued by exogenous chaperone CD147.

Andrina Stäubli et al.

Human molecular genetics, 26(21), 4203-4214 (2017-11-01)

Membrane transporters influence biological functions in the ocular lens. Here, we investigate the monocarboxylate transporter 12 (MCT12), also called creatine transporter 2 (CRT2), which is found in the ocular lens and is involved in cataract. As the age-related form affects

Estimated carrier frequency of creatine transporter deficiency in females in the general population using functional characterization of novel missense variants in the SLC6A8 gene.

Caro-Lyne DesRoches et al.

Gene, 565(2), 187-191 (2015-04-12)

Creatine transporter deficiency (CRTR-D) is an X-linked inherited disorder of creatine transport. All males and about 50% of females have intellectual disability or cognitive dysfunction. Creatine deficiency on brain proton magnetic resonance spectroscopy and elevated urinary creatine to creatinine ratio

Effects of a pre-workout supplement on hyperemia following leg extension resistance exercise to failure with different resistance loads.

Jeffrey S Martin et al.

Journal of the International Society of Sports Nutrition, 14, 38-38 (2017-09-30)

We sought to determine if a pre-workout supplement (PWS), containing multiple ingredients thought to enhance blood flow, increases hyperemia associated with resistance training compared to placebo (PBO). Given the potential interaction with training loads/time-under-tension, we evaluated the hyperemic response at

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Número de artículo de comercio global

SKU	GTIN
C3630-100G	04061833486061
C3630-1KG	04061833486078

Questions

1–2 of 2 Questions

Anonymous

10 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  10 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
  Helpful?

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