A0760
L-Azetidine-2-carboxylic acid
≥99%
Synonym(s):
(S)-Azetidine-2-carboxylic acid
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About This Item
Empirical Formula (Hill Notation):
C4H7NO2
CAS Number:
Molecular Weight:
101.10
UNSPSC Code:
12352209
NACRES:
NA.32
PubChem Substance ID:
EC Number:
218-362-5
Beilstein/REAXYS Number:
80680
MDL number:
Assay:
≥99%
Form:
powder
Pricing and availability is not currently available.
Quality Segment
assay
≥99%
form
powder
SMILES string
OC(=O)[C@@H]1CCN1
InChI
1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1
InChI key
IADUEWIQBXOCDZ-VKHMYHEASA-N
General description
L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.
Application
L-Azetidine-2-carboxylic acid has been used as a:
- collagen synthesis inhibitor
- protein folding antagonist
- as a standard in liquid chromatography-mass spectrometry
Biochem/physiol Actions
L-Azetidine-2-carboxylic acid is an inhibitor of collagen synthesis that is anti-angiogenic.
L-Azetidine-2-carboxylic acid is an inhibitor of collagen synthesis that is anti-angiogenic. It is a four-membered ring analog of L-proline that causes protein misconstruction when incorporated instead of proline.
Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.
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This Item | |||
|---|---|---|---|
| assay ≥99% | assay ≥99.5% (T) | assay ≥98% (TLC) | assay ≥99.0% (NT) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form powder | form powder or crystals | form powder | form powder or crystals |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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