1612539

Sertraline hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
• Formule empirique (notation de Hill) : C₁₇H₁₇NCl₂ · HCl
• Numéro CAS: 79559-97-0
• Poids moléculaire : 342.69
• NACRES: NA.24
• PubChem Substance ID: 329751093
• UNSPSC Code: 41116107
• MDL number: MFCD00895772

Propriétés

• grade: pharmaceutical primary standard
• agency: USP
• API family: sertraline
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: ClC1=C(Cl)C=CC([C@H]2C3=C(C=CC=C3)[C@@H](NC)CC2)=C1.[H]Cl
• InChI: 1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17-;/m0./s1
• InChI key: BLFQGGGGFNSJKA-XHXSRVRCSA-N
• Gene Information: human ... SLC6A4(6532)

Description

General description

Sertraline hydrochloride is a SSRI i.e selective serotonin reuptake inhibitor. It is mainly used in treating psychiatric disorders. It also is effective in treating hypotension occurring in disorders like neurocardiogenic syncope and idiopathic orthostatic hypotension which is affected by autonomic dysfunction.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sertraline hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Sertraline Hydrochloride Oral Solution
• Sertraline Hydrochloride Tablets

Biochem/physiol Actions

Selective serotonin reuptake inhibitor, antidepressant.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302,H373,H410
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
• Classe de stockage: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pcodes: P260 - P264 - P273 - P301 + P312 - P314 - P391