S2501

Spermidine trihydrochloride

From microbial,synthetic, ≥98% (TLC), nNOS inhibitor, powder

• Synonyme(s) : N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride
• Formule linéaire : NH₂(CH₂)₃NH(CH₂)₄NH₂ · 3HCl
• Numéro CAS: 334-50-9
• Poids moléculaire : 254.63
• NACRES: NA.32
• PubChem Substance ID: 24277993
• UNSPSC Code: 12352204
• EC Number: 206-379-0
• MDL number: MFCD00012918
• Beilstein/REAXYS Number: 3552356

Propriétés

• Nom du produit: Spermidine trihydrochloride, ≥98% (TLC)
• Quality Segment: 200
• biological source: microbial, synthetic
• assay: ≥98% (TLC)
• form: powder
• mp: 257-259 °C (lit.)
• solubility: water: 100 mg/mL, clear, colorless
• storage temp.: room temp
• SMILES string: Cl[H].Cl[H].Cl[H].NCCCCNCCCN
• InChI: 1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
• InChI key: LCNBIHVSOPXFMR-UHFFFAOYSA-N
• Gene Information: human ... NOS1(4842)

Description

General description

The nitric oxide synthase (nNOS) gene is localized on human chromosome 12q24.22. The enzyme is involved in the production of nitric oxide.

Application

Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves