A4929
N,N′-Bis(acryloyl)cystamine
BioReagent, suitable for electrophoresis
Synonyme(s) :
2,2′-(Bisacrylamino)diethyl disulfide, BAC, Bis(2-acrylamidoethyl) disulfide
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A propos de cet article
Formule empirique (notation de Hill) :
C10H16N2O2S2
Numéro CAS:
Poids moléculaire :
260.38
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
262-546-8
MDL number:
Form:
powder
Le tarif et la disponibilité ne sont pas disponibles actuellement.
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product line
BioReagent
form
powder
suitability
suitable for electrophoresis
storage temp.
−20°C
SMILES string
C=CC(=O)NCCSSCCNC(=O)C=C
InChI
1S/C10H16N2O2S2/c1-3-9(13)11-5-7-15-16-8-6-12-10(14)4-2/h3-4H,1-2,5-8H2,(H,11,13)(H,12,14)
InChI key
DJVKJGIZQFBFGS-UHFFFAOYSA-N
Application
BAC is used as a reversible cross-linker for polyacrylamide gels, to simplify isolation of macromolecules separated on the gels. The disulfide linkage can be broken with a suitable reducing agent. A 1-g slice of a 4% (12:1) gel will dissolve in 5 mL of 100 mM DTT in TBE (pH 8.3) in less than 30 min.
BAC is used as a reversible cross-linker for polyacrylamide gels. The disulfide linkage can be broken with a suitable reducing agent. A 12:1 ratio of acrylamide:BAC is recommended for DNA purification. A one gram slice of a 4% gel will dissolve in 5 mL of 100 mM DTT, TBE solution (pH 8.3) in less than 30 min. The pH of 8.3 is optimum for rapid dissolution of the gel.
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| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| form powder | form solid | form liquid | form solid |
| storage temp. −20°C | storage temp. - | storage temp. 2-30°C | storage temp. - |
| suitability suitable for electrophoresis | suitability - | suitability - | suitability - |
| product line BioReagent | product line - | product line - | product line - |
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Nick Orr et al.
Human molecular genetics, 24(10), 2966-2984 (2015-02-06)
We recently identified a novel susceptibility variant, rs865686, for estrogen-receptor positive breast cancer at 9q31.2. Here, we report a fine-mapping analysis of the 9q31.2 susceptibility locus using 43 160 cases and 42 600 controls of European ancestry ascertained from 52
Na-Yu Chia et al.
Gut, 64(5), 707-719 (2014-07-24)
Gastric cancer (GC) is a deadly malignancy for which new therapeutic strategies are needed. Three transcription factors, KLF5, GATA4 and GATA6, have been previously reported to exhibit genomic amplification in GC. We sought to validate these findings, investigate how these
David W Cescon et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(11), 2499-2505 (2015-03-06)
Genomic profiling of lung squamous cell carcinomas (SCC) has identified NRF2 pathway alterations, which activate oxidative response pathways, in one third of tumors. Preclinical data suggest these tumors may be resistant to platinum-based chemotherapy. We evaluated the clinical relevance of
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| A4929-5G | 04061833375259 |