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41639

Diméthylsulfoxyde

BioUltra, Molecular Biology, ≥99.5% (GC)

Synonyme(s) :

DMSO, Sulfoxyde de méthyle

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A propos de cet article

Formule linéaire :
(CH3)2SO
Numéro CAS:
67-68-5
Poids moléculaire :
78.13
UNSPSC Code:
12191502
NACRES:
NA.25
PubChem Substance ID:
57650076
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
MFCD00002089
Assay:
≥99.5% (GC)
Grade:
Molecular Biology
Technique(s):
GC/GC: suitable
Bp:
189 °C (lit.)
Vapor pressure:
0.42 mmHg ( 20 °C)
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grade

Molecular Biology

Quality Segment

200

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

product line

BioUltra

assay

≥99.5% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

GC/GC: suitable

impurities

Dnases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected, ≤0.001% free acid (as CH3COOH)

evapn. residue

≤0.005%

color

colorless

refractive index

n20/D 1.479

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H2O: miscible (completely)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

cation traces

Al: ≤0.5 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.1 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.05 mg/kg, Co: ≤0.02 mg/kg, Cr: ≤0.02 mg/kg, Cu: ≤0.02 mg/kg, Fe: ≤0.5 mg/kg, K: ≤0.5 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤0.1 mg/kg, Mn: ≤0.02 mg/kg, Mo: ≤0.1 mg/kg, Na: ≤1 mg/kg, Ni: ≤0.5 mg/kg, Pb: ≤0.1 mg/kg, Sr: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg

λ

neat

UV absorption

λ: 280 nm Amax: 0.22

suitability

suitable for molecular biology

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

General description

Le diméthylsulfoxyde (DMSO) est un solvant aprotique efficace. C'est un produit incolore, inodore et hygroscopique. Le DMSO augmente la perméabilité de divers perméants hydrophiles et lipophiles. C'est l'un des solvants couramment utilisés dans le laboratoire.

Application

Le diméthylsulfoxyde (DMSO) a été utilisé comme véhicule de composés à tester dans diverses études expérimentales.[1] Il a également été utilisé comme solvant dans le protocole d'agrégation de l'amyloïdeβ (Aβ) pour la resolubilisation du peptide en vue de maintenir son état dissocié.

Other Notes

Transfert génique assisté par polybrène/DMSO[2]

Disclaimer

Refroidit facilement et revient doucement à la température de la pièce. Les produits solides peuvent être reliquéfiés par chauffage à la température ambiante sans abîmer le produit.

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Cet article
D8418D5879276855
Dimethyl sulfoxide BioUltra, Molecular Biology, ≥99.5% (GC)

Sigma-Aldrich

41639

Dimethyl sulfoxide

Dimethyl sulfoxide Molecular Biology

Sigma-Aldrich

D8418

Dimethyl sulfoxide

Dimethyl sulfoxide ReagentPlus®, ≥99.5%

Sigma-Aldrich

D5879

Dimethyl sulfoxide

Dimethyl sulfoxide anhydrous, ≥99.9%

Sigma-Aldrich

276855

Dimethyl sulfoxide

technique(s)

GC/GC: suitable

technique(s)

DNA sequencing: suitable, PCR: suitable, transfection: suitable

technique(s)

immunoblotting: suitable

technique(s)

-

grade

Molecular Biology

grade

Molecular Biology

grade

-

grade

anhydrous

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥99.5% (GC)

assay

≥99.9%

assay

≥99.5%

assay

≥99.9%

solubility

H2O: miscible (completely)

solubility

H2O: miscible (completely)

solubility

H2O: soluble(lit.), acetone: soluble(lit.), benzene: soluble(lit.), chloroform: soluble(lit.), ethanol: soluble(lit.)

solubility

H2O: miscible (completely)

form

liquid

form

liquid

form

liquid

form

liquid

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Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificats d'analyse (COA)

Lot/Batch Number
BCCP1830
BCCM8451
BCCM1815
BCCL0999
BCCL9737

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

R Aubin et al.
Methods in molecular biology (Clifton, N.J.), 7, 35-43 (1991-01-01)
Efforts to expand the current repertory of cell types amenable to transfection have often been thwarted by a common obstacle-namely, the low tolerance displayed by the recipient cells toward the gene-transfer regimen itself. As a result, several laboratories have turned
Developmental toxicity assay using high content screening of zebrafish embryos
Lantz-McPeak S, et al.
Journal of Applied Toxicology, 35(3), 261-272 (2015)
Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons
Ungureanu A, et al.
Scientific reports, 6, 25841-25841 (2016)
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Numéro d'article de commerce international

RéférenceGTIN
667056-1G04061826699812
41639-100ML04061832089645
41639-500ML04061832089652

Questions

1–10 of 11 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is Dimethyl sulfoxide a sterile product?

    1 answer

    1. No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

      Helpful?

  4. Where does DMSO come from?

    1 answer

    1. DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

      Helpful?

  5. What is Sure/Seal™ packaging?

    1 answer

    1. The Aldrich Sure/Seal™ packaging system is useful in the handling and storage of air-sensitive reagents.

      Helpful?

  6. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    1 answer

    1. DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

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  7. What is the DMSO dissolved in?

    1 answer

    1. DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

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  8. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  9. What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

    1 answer

    1. DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.

      Helpful?

  10. Does DMSO have any synthetic utility?

    1 answer

    1. DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

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1–10 of 11 Questions  

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