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Key Documents

395B

Sigma-Aldrich

Periodic Acid-Schiff (PAS) Staining System

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About This Item

Code UNSPSC :
12352106
Nomenclature NACRES :
NA.47

Durée de conservation

Expiry date on the label.

IVD

for in vitro diagnostic use

Application(s)

hematology
histology

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Application

Standard procedure and microwave procedure included in package insert.
When treated with periodic acid, glycols are oxidized to aldehydes. After reaction with Schiff′s Reagent (a mixture of pararosaniline and sodium metabisulfite), a pararosaniline adduct is released that stains the glycol-containing cellular elements pink to red. Cellular elements which may be demonstrated with the PAS procedure include glycogen, fungal walls, basement membrane, certain epithelial sulfomucins and sialomucins, neutral mucosubstances, colloid material of the thyroid and the pars intermedia of the pituitary.

Composants de kit seuls

Réf. du produit
Description

  • Hematoxylin Solution, Gill No. 3 (kit only) 100 mL

  • Periodic Acid Solution (395-1) 2 x 100

  • Schiff's Reagent (kit only) 4 x 50

Pictogrammes

Health hazardCorrosionExclamation mark

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1 - STOT RE 2 Oral

Organes cibles

Kidney

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Ming Jiang et al.
Nature, 550(7677), 529-533 (2017-10-12)
In several organ systems, the transitional zone between different types of epithelium is a hotspot for pre-neoplastic metaplasia and malignancy, but the cells of origin for these metaplastic epithelia and subsequent malignancies remain unknown. In the case of Barrett's oesophagus
Tavia Caplan et al.
Cell chemical biology, 27(3), 269-282 (2020-01-12)
New strategies are urgently needed to counter the threat to human health posed by drug-resistant fungi. To explore an as-yet unexploited target space for antifungals, we screened a library of protein kinase inhibitors for the ability to reverse resistance of
Luke Whitesell et al.
Nature communications, 10(1), 402-402 (2019-01-27)
New strategies are needed to counter the escalating threat posed by drug-resistant fungi. The molecular chaperone Hsp90 affords a promising target because it supports survival, virulence and drug-resistance across diverse pathogens. Inhibitors of human Hsp90 under development as anticancer therapeutics
Anja Beckers et al.
Development (Cambridge, England), 147(21) (2020-05-08)
Cilia are complex cellular protrusions consisting of hundreds of proteins. Defects in ciliary structure and function, many of which have not been characterised molecularly, cause ciliopathies: a heterogeneous group of human syndromes. Here, we report on the FOXJ1 target gene
Angela C Nolin et al.
American journal of physiology. Renal physiology, 311(6), F1271-F1279 (2016-09-02)
Proteinuria is a major risk factor for chronic kidney disease progression. Furthermore, exposure of proximal tubular epithelial cells to excess albumin promotes tubular atrophy and fibrosis, key predictors of progressive organ dysfunction. However, the link between proteinuria and tubular damage

Articles

Fungal stains remain an important tool in the histology laboratory's diagnostic arsenal for identifying infectious microorganisms.

Fungal stains remain an important tool in the histology laboratory's diagnostic arsenal for identifying infectious microorganisms.

Fungal stains remain an important tool in the histology laboratory's diagnostic arsenal for identifying infectious microorganisms.

Fungal stains remain an important tool in the histology laboratory's diagnostic arsenal for identifying infectious microorganisms.

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