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51145

L-Tryptophane

Name: <SC>L</SC>-Tryptophane
Brand: SIAL

certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonyme(s) :

Acide L-α-amino-3-indolepropionique, Acide (S)-2-amino-3-(3-indolyl)propionique

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Conditionnement	Référence	Disponibilité	Prix

A propos de cet article

Formule empirique (notation de Hill) :

C₁₁H₁₂N₂O₂

Numéro CAS:

73-22-3

Poids moléculaire :

204.23

NACRES:

NA.24

PubChem Substance ID:

329757672

eCl@ss:

32160406

UNSPSC Code:

41116107

EC Number:

200-795-6

MDL number:

MFCD00064340

Beilstein/REAXYS Number:

86197

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Quality Level

300

product line

TraceCERT^®

grade

certified reference material, TraceCERT^®

analyte chemical class(es)

amino acids, peptides, proteins

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white

mp

280-285 °C (dec.) (lit.)

application(s)

food and beverages

format

neat

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Catégories apparentées

Chimie analytique

Étalons d'acides aminés, de peptides et de protéines

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1 of 1

Cet article	1700501	T8941	T0254
Supelco 51145 L-Tryptophan	USP 1700501 L-Tryptophan	Sigma-Aldrich T8941 L-Tryptophan	Sigma-Aldrich T0254 L-Tryptophan
application(s) food and beverages	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) cell analysis
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable	technique(s) -
format neat	format neat	format -	format -
Quality Level 300	Quality Level -	Quality Level 300	Quality Level 200
grade certified reference material, TraceCERT^®	grade pharmaceutical primary standard	grade -	grade reagent grade
manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland	manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename -

General description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Check out the entire portfolio of our amino acids certified reference materials (CRM)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Acide aminé précurseur de la sérotonine et de la mélatonine

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Store under Argon

Classe de stockage

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Glutathione and tryptophan metabolism are required for Arabidopsis immunity during the hypersensitive response to hemibiotrophs.

Kei Hiruma et al.

Proceedings of the National Academy of Sciences of the United States of America, 110(23), 9589-9594 (2013-05-23)

The hypersensitive response (HR) is a type of strong immune response found in plants that is accompanied by localized cell death. However, it is unclear how HR can block a broad range of pathogens with different infective modes. In this

On the mechanism of photoinduced dimer dissociation in the plant UVR8 photoreceptor.

Alexander A Voityuk et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(14), 5219-5224 (2014-03-19)

UV-B absorption by the photoreceptor UV resistance locus 8 (UVR8) consisting of two identical protein units triggers a signal chain used by plants in connection with protection and repair of UV-B induced damage. X-ray structural analysis of the purified protein

Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion.

Michael Platten et al.

Cancer research, 72(21), 5435-5440 (2012-10-24)

Tryptophan catabolism in cancer is increasingly being recognized as an important microenvironmental factor that suppresses antitumor immune responses. It has been proposed that the essential amino acid tryptophan is catabolized in the tumor tissue by the rate-limiting enzyme indoleamine-2,3-dioxygenase (IDO)

The effect of raising and lowering tryptophan levels on human mood and social behaviour.

Simon N Young

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 368(1615), 20110375-20110375 (2013-02-27)

Acute tryptophan depletion (ATD) studies indicate that low serotonin can lower mood and also increase aggression, although results vary somewhat between studies with similar participants. Lowering of mood after ATD is related to the susceptibility of the study participants to

Labelled alpha-methyl-L-tryptophan as a tracer for the study of the brain serotonergic system.

M Diksic

Journal of psychiatry & neuroscience : JPN, 26(4), 293-303 (2001-10-10)

The alpha-methyl-L-trypotophan (alpha-MTrp) method for the study of the brain serotonergic system is based on the fact that labelled alpha-MTrp is taken up by and, in part, retained in the brain, and this retention (trapping) is proportional to brain serotonin

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Numéro d'article de commerce international

Référence	GTIN
51145-1G	04061834232766
51145-100MG	04061832491271

Questions

1–2 of 2 Questions

Anonymous

9 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  9 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
  Helpful?

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