Key Documents

View All Documentation

Guanosine 3′,5′-cyclic monophosphate sodium salt

Name: Guanosine 3&#8242;,5&#8242;-cyclic monophosphate sodium salt
Brand: SIGMA

≥99% (HPLC), Cyclic nucleotide, powder

Synonym(s):

3′,5′-Cyclic GMP monosodium salt, 3′,5′-cGMP-Na, Guanosine 3′,5′-cyclophosphate monosodium salt, cGMP, cyclic GMP

Select a Size

Change View

Size/SKU	Availability	Price

About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₁N₅NaO₇P

CAS Number:

40732-48-7

Molecular Weight:

367.19

NACRES:

NA.77

PubChem Substance ID:

24895245

UNSPSC Code:

41106305

EC Number:

255-056-0

MDL number:

MFCD00038424

Beilstein/REAXYS Number:

6467425

Assay:

≥99% (HPLC)

Form:

powder

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Guanosine 3′,5′-cyclic monophosphate sodium salt, ≥99% (HPLC), powder

Quality Segment

200

assay

≥99% (HPLC)

form

powder

color

white

solubility

H₂O: 50 mg/mL

storage temp.

−20°C

SMILES string

[Na+].NC1=Nc2c(ncn2[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)C(=O)N1

InChI

1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-5(16)6-3(21-9)1-20-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

InChI key

KMPIYXNEROUNOG-GWTDSMLYSA-M

Description

Biochem/physiol Actions

An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases and PKA & PKG pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	G7504	203820	SML1229
Sigma-Aldrich G6129 Guanosine 3′,5′-cyclic monophosphate sodium salt	Sigma-Aldrich G7504 Guanosine 3′,5′-cyclic monophosphate	Sigma-Aldrich 203820 Guanosine 3′,5′-cyclic Monophosphate, 8-Bromo-, Sodium Salt	Sigma-Aldrich SML1229 2′,3′-cGAMP sodium salt
assay ≥99% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form powder	form powder	form solid	form powder
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
solubility H₂O: 50 mg/mL	solubility 0.2 M NaHCO₃: 50 mg/mL	solubility water: 200 mg/mL	solubility -
color white	color white	color white	color white to beige

Still not finding the right product?

Explore all of our products under Guanosine 3′,5′-cyclic monophosphate sodium salt

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.