1554705

Prazosin hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine hydrochloride, Furazosin hydrochloride
• Empirical Formula (Hill Notation): C₁₉H₂₁N₅O₄ · HCl
• CAS Number: 19237-84-4
• Molecular Weight: 419.86
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750933
• MDL number: MFCD00058177
• Beilstein/REAXYS Number: 4303561

Properties

• grade: pharmaceutical primary standard
• API family: prazosin
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: Cl.COc1cc2nc(nc(N)c2cc1OC)N3CCN(CC3)C(=O)c4ccco4
• InChI: 1S/C19H21N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22);1H
• InChI key: WFXFYZULCQKPIP-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

General description

Prazosin hydrochloride is an alpha-adrenergic blocking agent, employed as an antihypertensive drug for the treatment of high blood pressure. It lowers the blood pressure by binding to the alpha receptors thereby relaxing the blood vessels.

Application

It was used as an α₁-adrenergic receptors antagonist, in a study performed to understand the influence of dopamine on uterine motility of rats in vitro.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H336,H361fd,H373
• pcodes: P202 - P260 - P271 - P280 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Repr. 2 - STOT RE 2 - STOT SE 3
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• target_organs: Central nervous system