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T2879

Tyramine hydrochloride

≥98% (TLC), powder, neuromodulator

Synonym(s):

4-(2-Aminoethyl)phenol hydrochloride, 4-Hydroxyphenethylamine hydrochloride, Tyrosamine hydrochloride

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About This Item

Linear Formula:
HOC6H4CH2CH2NH2 · HCl
CAS Number:
60-19-5
Molecular Weight:
173.64
NACRES:
NA.77
PubChem Substance ID:
24277896
UNSPSC Code:
12352116
EC Number:
200-462-5
MDL number:
MFCD00012901
Beilstein/REAXYS Number:
3627058
Assay:
≥98%
Quality level:
200
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Product Name

Tyramine hydrochloride, ≥98%

Quality Level

200

assay

≥98%

mp

271-274 °C (lit.)

solubility

H2O: soluble 50 mg/ml, clear, colorless to faintly yellow

SMILES string

Cl[H].NCCc1ccc(O)cc1

InChI

1S/C8H11NO.ClH/c9-6-5-7-1-3-8(10)4-2-7;/h1-4,10H,5-6,9H2;1H

InChI key

RNISDHSYKZAWOK-UHFFFAOYSA-N

Gene Information

human ... ADORA2A(135), ADORA2B(136), ADORA3(140)

Application

Tyramine hydrochloride has been:
  • coinfused with adenosine in control subjects and patients in order to reduce leg blood flow by 50% without affecting arterial blood pressure[1]
  • labelled with fluorescence dyes (Atto 488 and Atto 655) to serve as a substrate for peroxidase in immunofluorescence analysis
  • used in dimethylformamide, labelled with 5-(and-6)carboxyfluorescein, succinimidyl ester/biotin to serve as a substrate for peroxidase in tyramide signal amplification

Biochem/physiol Actions

Can enter catecholaminergic terminals and be released as a false transmitter.
Tyramine is a biogenic amine and a neuromodulator localized to the nervous system. Tyrosine decarboxylase catalysis the formation of tyramine from tyrosine. Tyramine is found to be associated with a number of psychiatric disorders. Tyramine ingestion depletes serotonin, epinephrine and norepinephrine reserves. This results in elevated biological events such as cardiovascular function, blood pressure, glucose production and overall metabolism. It also causes depression, migraine and insomnia. Tyramine is present is several food sources. The process of food fermentation and spoilage increases its tyramine content.

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This Item
M4251M6500SML1924
Tyramine hydrochloride ≥98%

Sigma-Aldrich

T2879

Tyramine hydrochloride

3-Methoxytyramine hydrochloride ≥95.5%, crystalline

Sigma-Aldrich

M4251

3-Methoxytyramine hydrochloride

Cysteamine hydrochloride ≥98% (titration)

Sigma-Aldrich

M6500

Cysteamine hydrochloride

T1AM ≥98% (HPLC)

Sigma-Aldrich

SML1924

T1AM

assay

≥98%

assay

≥95.5%

assay

≥98% (titration)

assay

≥98% (HPLC)

solubility

H2O: soluble 50 mg/ml, clear, colorless to faintly yellow

solubility

-

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

solubility

H2O: 10 mg/mL, clear

mp

271-274 °C (lit.)

mp

213-215 °C (lit.)

mp

67-71 °C

mp

-

Gene Information

human ... ADORA2A(135), ADORA2B(136), ADORA3(140)

Gene Information

human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)

Gene Information

-

Gene Information

-

Quality Level

200

Quality Level

100

Quality Level

300

Quality Level

100

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM6821
BCCK6797
BCCH9984
BCCC3152
BCCB2324

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Two functional but noncomplementing Drosophila tyrosine decarboxylase genes distinct roles for neural tyramine and octopamine in female fertility
Cole Shannon H, et al.
Test, 280(15), 14948-14955 (2005)
Immunostaining Enhancement
Immunohistochemistry: Basics and Methods, 47-59 (2009)
Sepideh Saghati et al.
BMC research notes, 14(1), 384-384 (2021-09-30)
We aimed to detect the effect of a couple of parameters including Alg, H2O2, and HRP concentrations on the gelation time of Alg-based hydrogels using an enzymatic cross-linked procedure. NMR, UV-Vis, and ATR-FTIR analyses confirmed the conjugation of Ph to
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Global Trade Item Number

SKUGTIN
T2879-25G04061837343438
T2879-5G04061837343445
T2879-100G04061832093932
T2879-10MG04061837343414
T2879-1G04061837343421

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