This product may be stored in room temperature.
P5556
Poloxamer 188 solution
10%, sterile-filtered, BioReagent, suitable for insect cell culture
Synonym(s):
Nonionic copolymer surfactant
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About This Item
CAS Number:
UNSPSC Code:
12161902
PubChem Substance ID:
NACRES:
NA.75
MDL number:
Pricing and availability is not currently available.
description
non-ionic
Quality Level
sterility
sterile-filtered
product line
BioReagent
mol wt
average mol wt 8350
concentration
10%
technique(s)
cell culture | insect: suitable
impurities
endotoxin, tested
transition temp
cloud point ≥100
HLB
29
SMILES string
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
General description
Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.[1]
Application
A nonionic copolymer surfactant
Biochem/physiol Actions
Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence.[1][2] P-188 exhibits low toxicity and may be used in oral drug delivery.
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This Item | |||
|---|---|---|---|
| technique(s) cell culture | insect: suitable | technique(s) API processing | nano-milling: suitable | technique(s) - | technique(s) - |
| mol wt average mol wt 8350 | mol wt - | mol wt - | mol wt - |
| product line BioReagent | product line EMPROVE® EXPERT | product line - | product line - |
| description non-ionic | description - | description - | description - |
| Quality Level 400 | Quality Level 500 | Quality Level 100 | Quality Level - |
| HLB 29 | HLB - | HLB - | HLB - |
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Dina Mourad Saleh et al.
Particle and fibre toxicology, 17(1), 48-48 (2020-10-16)
Multi-walled carbon nanotubes can be divided into two general subtypes: tangled and straight. MWCNT-N (60 nm in diameter) and MWCNT-7 (80-90 nm in diameter) are straight-type MWCNTs, and similarly to asbestos, both are carcinogenic to the lung and pleura when administered to
Daniel Helman et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 85(2), 162-168 (2013-06-15)
We developed a membrane bound reporter and selection molecule for sorting by fluorescence activated cell sorting (FACS) of cells producing a protein of interest. This molecule is composed of a transmembrane (TM) domain, fused on its extracellular end to a
Rahul P Bakshi et al.
Nature communications, 9(1), 315-315 (2018-01-24)
Chemoprophylaxis is currently the best available prevention from malaria, but its efficacy is compromised by non-adherence to medication. Here we develop a long-acting injectable formulation of atovaquone solid drug nanoparticles that confers long-lived prophylaxis against Plasmodium berghei ANKA malaria in
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5556-4L | 04061837036224 |
| P5556-100ML | 04061834391937 |
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what is the storage temperature for this product
1 answer-
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What is this compound dissolved in ? I can not see any information about that.
1 answer-
This product is a 10% solution of Poloxamer 188 in water.
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How does the pH of the Poloxamer 188 solution fluctuate throughout a 24-month period?
1 answer-
The pH of a solution containing Poloxamer 188 may change over time due to factors such as hydrolysis or oxidation. The pH stability of Poloxamer 188 solutions has not been conducted. However, end users are encouraged to periodically monitor the solutions to ensure their stability and efficacy.
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