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M9271

α-D-Mannopyranosylphenyl isothiocyanate

>98% (TLC)

Synonym(s):

4-Isothiocyanatophenyl-α-D-mannopyranoside

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About This Item

Empirical Formula (Hill Notation):
C13H15NO6S
CAS Number:
96345-79-8
Molecular Weight:
313.33
NACRES:
NA.25
PubChem Substance ID:
24897324
UNSPSC Code:
12352201
MDL number:
MFCD00070374
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Quality Level

100

assay

>98% (TLC)

form

powder

technique(s)

thin layer chromatography (TLC): suitable

impurities

≤5% water (Karl Fischer)

color

white to off-white

solubility

50 mg/mL, clear to very slightly hazy, colorless to light yellow (ACETONE:DIMETHYL SULFOXIDE (7:3))

storage temp.

2-8°C

SMILES string

OCC1OC(Oc2ccc(cc2)N=C=S)C(O)C(O)C1O

InChI

1S/C13H15NO6S/c15-5-9-10(16)11(17)12(18)13(20-9)19-8-3-1-7(2-4-8)14-6-21/h1-4,9-13,15-18H,5H2

InChI key

RWANFUZQWINQBY-UHFFFAOYSA-N

Application

α-D-Mannopyranosylphenyl isothiocyanate has been used in a study to assess the effect of antigen delivery using a novel mannosylated dendrimer. [1] It has also been used in a study to improve gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item
A1394G0259I5502
α-D-Mannopyranosylphenyl isothiocyanate >98% (TLC)

Sigma-Aldrich

M9271

α-D-Mannopyranosylphenyl isothiocyanate

4-Aminophenyl α-D-mannopyranoside ≥98% (TLC)

Sigma-Aldrich

A1394

4-Aminophenyl α-D-mannopyranoside

D-Glucosaminic acid ≥98% (TLC)

Sigma-Aldrich

G0259

D-Glucosaminic acid

Isopropyl β-D-1-thiogalactopyranoside ≥99% (TLC)

Sigma-Aldrich

I5502

Isopropyl β-D-1-thiogalactopyranoside

assay

>98% (TLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥99% (TLC)

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

technique(s)

thin layer chromatography (TLC): suitable

solubility

50 mg/mL, clear to very slightly hazy, colorless to light yellow (ACETONE:DIMETHYL SULFOXIDE (7:3))

solubility

H2O: soluble

solubility

0.5 M HCl: 50 mg/mL, clear, colorless to faintly yellow

solubility

water: 50 mg/mL, clear, colorless

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200, 300

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000529219
0000529219
0000414167
0000414167
0000369366

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Improvement of gene delivery mediated by mannosylated dendrimer/α-cyclodextrin conjugates
Wada, K., et al.
J. Controlled Release, 104, 397-413 (2005)
Kuo-Ching Sheng et al.
European journal of immunology, 38(2), 424-436 (2008-01-18)
Antigen mannosylation has been shown to be an effective approach to potentiate antigen immunogenicity, due to the enhanced antigen uptake and presentation by APC. To overcome disadvantages associated with conventional methods used to mannosylate antigens, we have developed a novel
M Monsigny et al.
Biology of the cell, 51(2), 187-196 (1984-01-01)
The presence and the sugar specificity of membrane lectins on the cell surface of mouse L1210 leukemia cells were demonstrated by using various neoglycoproteins (glycosylated serum albumin) substituted with fluorescein or methotrexate. Neoglycoproteins were prepared by reaction of glycosidophenylisothiocyanates with

Global Trade Item Number

SKUGTIN
M9271-25MG04061834064121
M9271-10MG04061834064114

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