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I5161

Iodoacetamide

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About This Item

Linear Formula:
ICH2CONH2
CAS Number:
144-48-9
Molecular Weight:
184.96
EC Number:
205-630-1
UNSPSC Code:
12352202
NACRES:
NA.21
Beilstein/REAXYS Number:
1739080
MDL number:
MFCD00008028
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biological source

synthetic

Quality Level

400

assay

≥99% (NMR)

form

powder

mp

92-95 °C (lit.)

solubility

H2O: 0.5 M, clear, colorless

suitability

suitable for manufacturing use

storage temp.

2-8°C

SMILES string

NC(=O)CI

InChI

1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)

InChI key

PGLTVOMIXTUURA-UHFFFAOYSA-N

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Biochem/physiol Actions

Iodoacetamide acts as an alkylating reagent for cysteine residues in peptide sequencing. It is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibiting ribonuclease.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
A3221I6125I1149
Iodoacetamide

SAFC

I5161

Iodoacetamide

Iodoacetamide Single use vial of 56 mg

Sigma-Aldrich

A3221

Iodoacetamide

Iodoacetamide ≥99% (NMR), crystalline

Sigma-Aldrich

I6125

Iodoacetamide

Iodoacetamide BioUltra

Sigma-Aldrich

I1149

Iodoacetamide

form

powder

form

powder

form

crystalline

form

powder

biological source

synthetic

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

assay

≥99% (NMR)

assay

≥99% (HPLC)

assay

≥99% (NMR)

assay

≥99% (NMR)

suitability

suitable for manufacturing use

suitability

suitable for LC-MS

suitability

-

suitability

-

Quality Level

400

Quality Level

200

Quality Level

300

Quality Level

300

solubility

H2O: 0.5 M, clear, colorless

solubility

H2O: soluble 50 mg/mL, clear, colorless to faintly yellow

solubility

H2O: soluble 0.5 M, clear, colorless

solubility

H2O: 0.5 M, clear, colorless

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000560816
0000560817
0000529196
0000529196
0000560817

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Valentina R Minciacchi et al.
Oncotarget, 6(13), 11327-11341 (2015-04-11)
Large oncosomes (LO) are atypically large (1-10 µm diameter) cancer-derived extracellular vesicles (EVs), originating from the shedding of membrane blebs and associated with advanced disease. We report that 25% of the proteins, identified by a quantitative proteomics analysis, are differentially
Mia Jüllig et al.
PloS one, 9(5), e96489-e96489 (2014-05-08)
Bypass of foregut secreted factors promoting insulin resistance is hypothesized to be one of the mechanisms by which resolution of type 2 diabetes (T2D) follows roux-en-y gastric bypass (GBP) surgery. To identify insulin resistance-associated proteins and metabolites which decrease more
Jeremy Rouillon et al.
Neuromuscular disorders : NMD, 24(7), 563-573 (2014-05-13)
Diagnosis of muscular dystrophies is currently based on invasive methods requiring muscle biopsies or blood tests. The aim of the present study was to identify urinary biomarkers as a diagnostic tool for muscular dystrophies. Here, the urinary proteomes of Duchenne
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Global Trade Item Number

SKUGTIN
I5161-10KG04065267543420
I5161-100G04061832608532
I5161-25G04061832608549

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