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H4397

TiterMax® Classic Adjuvant

liquid

Synonym(s):

Adjuvant System, TiterMax Adjuvant

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About This Item

NACRES:
NA.46
UNSPSC Code:
12352203
Pricing and availability is not currently available.
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form

liquid

Quality Level

availability

not available in Japan

storage temp.

2-8°C

General description

The effectiveness of an oil emulsion vaccine greatly depends on the form and stability of the emulsion. TiterMax Classic is a water-in-oil formulation with up to 90% water and a powerful adjuvant used in many protocols. TiterMax Classic Adjuvant contains three essential ingredients: a block copolymer, CRL89-41, squalene (a metabolizable oil) and a unique microparticulate stabilizer. The emulsion is less viscous and suitable for injection through small needles.

Application

TiterMax® Classic Adjuvant has been used to boost the production of antigen-specific polyclonal IgG in rabbits.
For mice, four doses of 10 microl each into subcutaneous or muscular sites is recommended. TiterMax® was used in mice followed by isolation of CD4 T cells for epitope mapping[1] and to test vaccines against Neisseria species.[2]

Biochem/physiol Actions

TiterMax Classic has been especially formulated with squalene to produce stable water-in-oil emulsions with up to 90% water. It is considerably easier to emulsify TiterMax Classic than Freund′s adjuvant. The resulting emulsion is less viscous, making it easier to inject through small needles.

Legal Information

TiterMax is a registered trademark of TiterMax USA, Inc

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item
T2684344291344289
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

liquid

form

liquid

form

liquid (oily)

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

10-30°C

storage temp.

2-8°C

availability

not available in Japan

availability

not available in Japan

availability

-

availability

-


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Related Content

Instructions


Preclinical efficacy and immunogenicity assessment to show that a chimeric Plasmodium falciparum UB 05-09 antigen could be a malaria vaccine candidate
Dinga JN, et al.
Parasite Immunology, 40(3), e12514-e12514 (2018)
A A Delvig et al.
Methods in molecular medicine, 66, 349-360 (2001-01-01)
The majority of T cells recognize peptide epitopes bound to major histocompatibility complex (MHC)-encoded glycoproteins on the surface of professional antigen-presenting cells (APC), principally dendritic cells, macrophages, and B cells (1-3). Most T cells are specific for peptide epitopes in
A A Delvig et al.
Methods in molecular medicine, 66, 199-221 (2001-01-01)
Proteins with intrinsic mitogenic properties are widely represented in prokaryotes, such as in different Streptococcus species (1-3), Candida albicans (4), and Eikenella corrodens (5). Specifically, several bacterial porins of Escherichia coli, Shigella dysenteriae, Salmonella typhimurium, Fusobacterium nucleatum, and pathogenic Neisseria



Global Trade Item Number

SKUGTIN
H4397-.5ML04061833795194

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