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G7516

γ-Globulins from bovine blood

≥97% (agarose gel electrophoresis)

Synonym(s):

Bovine γ-Globulin

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About This Item

CAS Number:
MDL number:
EC Number:
232-706-1
NACRES:
NA.61
UNSPSC Code:
12352202
Form:
powder
Assay:
≥97% (agarose gel electrophoresis)
Biological source:
bovine blood
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biological source

bovine blood

Quality Segment

assay

≥97% (agarose gel electrophoresis)

form

powder

composition

NaCl, ≤5%

solubility

0.9% NaCl: soluble 50 mg/mL

storage temp.

−20°C

General description

Bovine gamma globulin (BGG) is an important component of the immune system of cows and other bovines. BGG is found in the blood of bovines and is primarily used in the production of medical products such as vaccines, serums, and diagnostic reagents. BGG can also be used to treat certain medical conditions, such as hepatitis B, as well as to boost immunity in humans and other animals.
Plasma protein fraction rich in antibodies
The γG globulins of bovine serum are categorized by anion exchange chromatography, immunoelectrophoresis, zone electrophoresis, ultracentrifugation, and analysis of the products of papain digestion. They have properties similar to analogous components of human serum. This was determined by the methods such as: gel filtration, immunoelectrophoresis, anion exchange chromatography, ultracentrifugation, and reduction with mercaptoethanol. Fast and slow γG globulins were classified on the basis of differences in electrophoretic migration rates, chromatographic elution positions, and biological activities (complement fixation). Bovine γA was conditionally found in immunoelectrophoretic analyses of serum and chromatographic fractions.

Application

Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.
γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.[1]
Bovine γ-globulins were used to study the constituents and pH changes in protein rich hyaluronan solution affecting the bio-tribological properties of artificial articular joints.[2] It is also used to determine immunoglobulin G in bovine colostrum and milk by direct biosensor SPR-immunoassay.
Bovine γ-globulin was used in rapid screening for monensin residues in poultry plasma by a dry reagent dissociation enhanced lanthanide fluoroimmunoassay.[3] It was also tested for the effects of solution properties on solute and permeate flux in bovine serum albumin-IgG ultrafiltration. [4]

Preparation Note

Prepared from plasma

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This Item
G5009H1000000Y0000488
assay

≥97% (agarose gel electrophoresis)

assay

≥99% (agarose gel electrophoresis)

assay

-

assay

-

biological source

bovine blood

biological source

bovine blood

biological source

-

biological source

-

form

powder

form

powder

form

-

form

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

0.9% NaCl: soluble 50 mg/mL

solubility

0.9% NaCl: soluble 25 mg/mL

solubility

-

solubility

-

Quality Level

300

Quality Level

300

Quality Level

-

Quality Level

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

  1. what is the molecular weight of this product? G7516-1G

    1 answer
    1. The molecular weight of this product is not determined. However, bovine gamma globulins will have a molecular weight range of 150 - 200 kDa.

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