42597

3′-Deoxythymidine 5′-triphosphate sodium salt solution

BioChemika, puriss. p.a., suitable for MALDI-MS, ≥98.0% (HPLC)

• Synonym(s): 2′,3′-Dideoxythymidine 5′-triphosphate, ddTTP
• Empirical Formula (Hill Notation): C₁₀H₁₆N₂NaO₁₃P₃
• CAS Number: 128524-26-5
• Molecular Weight: 488.15
• UNSPSC Code: 41116105
• PubChem Substance ID: 329756245
• MDL number: MFCD00079155

Properties

• product line: BioChemika
• grade: puriss. p.a.
• assay: ≥98.0% (HPLC)
• concentration: 10.0-11.0 mmol/L (UV)
• technique(s): MALDI-MS: suitable
• impurities: ≤1.5% ddNDP (HPLC)
• suitability: corresponds for UV test
• storage temp.: −20°C
• SMILES string: [Na+].CC1=CN([C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O
• InChI: 1S/C10H17N2O13P3.Na/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(23-8)5-22-27(18,19)25-28(20,21)24-26(15,16)17;/h4,7-8H,2-3,5H2,1H3,(H,18,19)(H,20,21)(H,11,13,14)(H2,15,16,17);/q;+1/p-1/t7-,8+;/m0./s1
• InChI key: QJSZKDPCBDXBCK-KZYPOYLOSA-M

Description

General description

3′-Deoxythymidine 5′-triphosphate sodium (ddTTP) is a sugar-modified dTTP analogue which is selective inhibitor of HIV-associated reverse transcriptase (HIV-RT).[1] It is also seen to inhibit the activity of DNA polymerase α.[2]

Packaging

packaging : 1 μmol (approx. 91-100 μL)

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)