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Levocarnitine

Name: Levocarnitine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

L-Carnitine inner salt, (−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, Vitamin B_T

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About This Item

Linear Formula:

(CH₃)₃N⁺CH₂CH(OH)CH₂COO^-

CAS Number:

541-15-1

Molecular Weight:

161.20

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750039

MDL number:

MFCD00038747

Beilstein/REAXYS Number:

4292315

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Properties

grade

pharmaceutical primary standard

agency

USP

API family

levocarnitine

manufacturer/tradename

USP

mp

197-212 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C[N+](C)(C)C[C@H](O)CC([O-])=O

InChI

1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1

InChI key

PHIQHXFUZVPYII-ZCFIWIBFSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Levocarnitine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

Levocarnitine Tablets
Levocarnitine Injection
Levocarnitine Oral Solution

Biochem/physiol Actions

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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This Item	L0399900	PHR1569	1359925
USP 1359903 Levocarnitine	L0399900 Levocarnitine	Supelco PHR1569 Levocarnitine	USP 1359925 Levocarnitine Related Compound A
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename -	manufacturer/tradename USP
format neat	format neat	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
mp 197-212 °C (lit.)	mp 197-212 °C (lit.)	mp 197-212 °C (lit.)	mp -
API family levocarnitine	API family levocarnitine	API family levocarnitine	API family levocarnitine

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Gestational age and age at sampling influence metabolic profiles in premature infants.

Reese H Clark et al.

Pediatrics, 134(1), e37-e46 (2014-06-11)

To describe the influence that gestational age and chronological age have on amino acid and acylcarnitine profiles in an at-risk population of premature infants. Metabolic profiles (15 amino acids and 35 acylcarnitines) were obtained by using standard newborn techniques on

Plasma acylcarnitines inadequately reflect tissue acylcarnitine metabolism.

Marieke G Schooneman et al.

Biochimica et biophysica acta, 1841(7), 987-994 (2014-04-22)

Acylcarnitines have been linked to obesity-induced insulin resistance. However the majority of these studies have focused on acylcarnitines in plasma. It is currently unclear to what extent plasma levels of acylcarnitines reflect tissue acylcarnitine metabolism. We investigated the correlation of

The effectiveness of taurine and levocarnitine in dogs with heart disease.

P D Pion et al.

The Veterinary clinics of North America. Small animal practice, 28(6), 1495-1514 (1999-03-31)

In this article, the current state of knowledge of the potential role of taurine and L-carnitine deficiency and supplementation in the genesis and management of cardiovascular disease in dogs is presented. There is limited direct evidence to support the recommendations

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Global Trade Item Number

SKU	GTIN
1359903-400MG	04061838731067

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