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1046205

USP

Aztreonam

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

[2S-[2α,3β(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid

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About This Item

Empirical Formula (Hill Notation):
C13H17N5O8S2
CAS Number:
Molecular Weight:
435.43
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

aztreonam

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

C[C@H]1[C@H](NC(=O)\C(=N/OC(C)(C)C(O)=O)c2csc(N)n2)C(=O)N1S(O)(=O)=O

InChI

1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1

InChI key

WZPBZJONDBGPKJ-VEHQQRBSSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aztreonam USP reference standard is meant to use for specified quality tests and assays.

Also used to prepare standard and system suitability solutions for assay according to the given below monographs of United States Pharmacopeia (USP):
  • Aztreonam
  • Aztreonam for Injection
  • Aztreonam Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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This Item
A6848PZ00381046307
manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

manufacturer/tradename

USP

grade

pharmaceutical primary standard

grade

analytical standard

grade

-

grade

pharmaceutical primary standard

application(s)

pharmaceutical (small molecule)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

application(s)

-

application(s)

pharmaceutical (small molecule)

format

neat

format

-

format

-

format

neat

API family

aztreonam

API family

-

API family

-

API family

aztreonam

storage temp.

−20°C

storage temp.

-

storage temp.

room temp

storage temp.

-


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Certificates of Analysis (COA)

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Aztreonam Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 462-462 (2018)
Aztreonam for Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 463-463 (2018)
Baroukh Maurice Assael
Expert review of anti-infective therapy, 9(11), 967-973 (2011-10-28)
An aerosol form of aztreonam lysinate has recently been developed as a treatment for cystic fibrosis patients suffering from chronic Pseudomonas aeruginosa lung colonization. Local administration means the drug can reach mucus concentrations in the order of hundreds of times



Global Trade Item Number

SKUGTIN
1046205-200MG04061833859285

Questions

  1. quelle est la solubilité de ce produit et ds quel solvant et eau ? Merci

    1 answer
    1. This is a product of the United States Pharmacopeia. Solubility testing has not been performed. However, the research product A6848 is tested for solubility at 50 mg/ml in a 1:1 mixture of dimethylformamide and methanol. Another research grade item, PZ0038, is tested for solubility at 2 mg/mL in DMSO. The solubility in water has not been determined.

      Please see the link below to review the datasheet for the research grade material, A6848:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/320/622/a6848pis.pdf

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