1005004

Acetazolamide

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide, N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide, N-(5-[Aminosulfonyl]-1,3,4-thiadiazol-2-yl)acetamide
• Empirical Formula (Hill Notation): C₄H₆N₄O₃S₂
• CAS Number: 59-66-5
• Molecular Weight: 222.25
• NACRES: NA.24
• PubChem Substance ID: 329748132
• UNSPSC Code: 41116107
• MDL number: MFCD00003105

Properties

• grade: pharmaceutical primary standard
• API family: acetazolamide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CC(=O)Nc1nnc(s1)S(N)(=O)=O
• InChI: 1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
• InChI key: BZKPWHYZMXOIDC-UHFFFAOYSA-N
• Gene Information: human ... CA1(759), CA12(771), CA2(760), CA4(762)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Acetazolamide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Acetazolamide Compounded Oral Suspension
• Acetazolamide Extended-Release Capsules
• Acetazolamide for Injection
• Acetazolamide Tablets

Carbonic anhydrase inhibitor; increases cerebral blood flow.

Biochem/physiol Actions

Inhibits water permeability of membranes by interacting with aquaporins

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable