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N-Benzoyl-Pro-Phe-Arg-p-nitroanilide hydrochloride

Name: N-Benzoyl-Pro-Phe-Arg-<I>p</I>-nitroanilide hydrochloride
Brand: SIGMA

protease substrate, chromogenic, ≥97% (HPLC), powder

Synonym(s):

Bz-Pro-Phe-Arg-p-nitroanilide hydrochloride, Bz-Pro-Phe-Arg-pNA hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₃₃H₃₈N₈O₆ · HCl

CAS Number:

59188-28-2

Molecular Weight:

679.17

UNSPSC Code:

12352204

PubChem Substance ID:

24891630

NACRES:

NA.32

MDL number:

MFCD00039010

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Properties

Product Name

N-Benzoyl-Pro-Phe-Arg-p-nitroanilide hydrochloride, protease substrate

Quality Segment

200

assay

≥97% (HPLC)

form

powder

solubility

methanol: 25 mg/mL

storage temp.

−20°C

SMILES string

Cl.NC(=N)NCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C2CCCN2C(=O)c3ccccc3)C(=O)Nc4ccc(cc4)N(=O)=O

InChI

1S/C33H38N8O6.ClH/c34-33(35)36-19-7-13-26(29(42)37-24-15-17-25(18-16-24)41(46)47)38-30(43)27(21-22-9-3-1-4-10-22)39-31(44)28-14-8-20-40(28)32(45)23-11-5-2-6-12-23;/h1-6,9-12,15-18,26-28H,7-8,13-14,19-21H2,(H,37,42)(H,38,43)(H,39,44)(H4,34,35,36);1H

InChI key

OGYWLWIIQPDFPW-UHFFFAOYSA-N

Description

General description

A chromogenic substrate for Agkistrodon contortrix thrombin-like enzyme and plasma kallikrein.[1][2]

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This Item	87528	B7260	T0273
Sigma-Aldrich B2133 N-Benzoyl-Pro-Phe-Arg-p-nitroanilide hydrochloride	Sigma-Aldrich 87528 N_α-Benzoyl-L-isoleucyl-L-glutamyl-glycyl-L-arginine-4-nitroanilide	Sigma-Aldrich B7260 N_α-Benzoyl-L-arginine-7-amido-4-methylcoumarin hydrochloride	Sigma-Aldrich T0273 N-p-Tosyl-Gly-Pro-Arg 7-amido-4-methylcoumarin hydrochloride
assay ≥97% (HPLC)	assay ≥97.0% (HPLC)	assay ≥99% (TLC)	assay ≥98% (TLC)
solubility methanol: 25 mg/mL	solubility -	solubility DMSO:methanol (1:1): 20 mg/mL, clear, colorless	solubility acetic acid: 10 mg/mL, clear, colorless
Quality Level 200	Quality Level 100	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000511455

0000511454

0000486957

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Global Trade Item Number

SKU	GTIN
B2133-100MG	04061833426593
B2133-5MG	04061833426609
B2133-25MG	04061835511792

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