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Dextrorphan

Name: Dextrorphan
Brand: SIGMA

NMDA glutamate receptor antagonist, solid

Synonym(s):

(+)-3-Hydroxy-17-methylmorphinan, 1,3,4,9,10,10a-Hexahydro-6-hydroxy-2H-10,4a-(iminoethano)-11-methylphenanthrene

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₃NO

CAS Number:

125-73-5

Molecular Weight:

257.37

NACRES:

NA.77

PubChem Substance ID:

24724648

UNSPSC Code:

12161501

EC Number:

204-754-3

MDL number:

MFCD00864199

Form:

solid

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Properties

Product Name

Dextrorphan,

form

solid

Quality Segment

200

optical activity

[α]/D ≥+54°

color

white to off-white

mp

≥195 °C

solubility

saline: soluble(lit.)

storage temp.

2-8°C

SMILES string

CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc4ccc(O)cc34

InChI

1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m1/s1

InChI key

JAQUASYNZVUNQP-PVAVHDDUSA-N

Gene Information

human ... GRIN2A(2903)
rat ... Grin2a(24409)

Description

Application

Dextrorphan has been studies as an N-methyl-D-aspartate (NMDA) receptor antagonist in Xenopus oocytes and hippocampal neuron cultures[1].

CYP2D6 O-Demethyl metabolite of dextromethorphan

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Preparation Note

Dextrorphan is soluble in water[1].

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This Item	SML1468	L5143	D127
Sigma-Aldrich UC205 Dextrorphan	Sigma-Aldrich SML1468 Dienogest	Sigma-Aldrich L5143 Levorphanol (+)-tartrate salt dihydrate	Sigma-Aldrich D127 Dextrorphan tartrate
form solid	form powder	form powder	form powder
Quality Level 200	Quality Level 100	Quality Level 200	Quality Level 200
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. -	storage temp. -
solubility saline: soluble(lit.)	solubility DMSO: 5 mg/mL, clear (warmed)	solubility H₂O: >20 mg/mL	solubility H₂O: >10 mg/mL
color white to off-white	color white to beige	color white	color white
Gene Information human ... GRIN2A(2903) rat ... Grin2a(24409)	Gene Information -	Gene Information -	Gene Information human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Global Trade Item Number

SKU	GTIN
UC205-10MG	04061832931890
UC205-5MG	04061832931906

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