F1177

Fluorescein hyaluronic acid

>95%, powder

• Synonym(s): Hyaluronic Acid Fluorescein Conjugate
• UNSPSC Code: 12352201
• NACRES: NA.25
• MDL number: MFCD00677027

Properties

• Quality Segment: 100
• assay: >95%
• form: powder
• mol wt: ~800,000 Da
• color: orange
• solubility: H₂O: soluble 1 mg/mL
• storage temp.: 2-8°C

Description

Application

Fluorescein hyaluronic acid has been used in the fluorescence imaging of hyaluronic acid (HA) and dextran surface coated filmsand patterned surfaces. It has also been used in confocal fluorescence microscopy to localize hyaluronic acid in collagen/HA composite gels .

Biochem/physiol Actions

Hyaluronan macromolecules (HAs) coupled to fluorescein amine is exploited to screen the hyaluronidase activity using fluorescence correlation spectroscopy (FCS) by measuring the quenching of fluorescein-labeled HA fragments. It binds on cell surface of malignant mesothelioma derived from human tumors.

Used to bind on cell surface of malignant mesothelioma derived from human tumors.

Other Notes

From cock′s comb or by fermentation.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)