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Collagen from rabbit skin

Name: Collagen from rabbit skin
Brand: SIGMA

Bornstein and Traub Type I, powder

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About This Item

CAS Number:

9007-34-5

UNSPSC Code:

12352202

EC Number:

232-697-4

NACRES:

NA.61

MDL number:

MFCD00130825

Form:

powder

Biological source:

rabbit skin

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Properties

biological source

rabbit skin

Quality Segment

200

description

acid soluble

form

powder

technique(s)

cell culture | stem cell: suitable

solubility

aqueous acid: ≤10 mg/mL, aqueous sodium acetate buffer: soluble (0.01-0.5M)

UniProt accession no.

Q28668

storage temp.

2-8°C

Gene Information

rabbit ... COL1A2(100008997)

Description

General description

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.

Application

Collagen-type 1 may be used in research of Idiopathic pulmonary fibrosis (IPF). Robust expression of collagen-type 1 is one distinctive feature of IPF. Additionally, collagen-type 1 has been used in studies on the effect of endoplasmic reticulum (ER) stress from IPF on myofibroblastic differentiation of lung fibroblasts. Collage-type 1 soluble in acidic solution produces three dimensional scaffolding useful in bioengineering and cell culture applications where biomaterials are needed to replace native collagen extracellular matrices.

Collagen Type I has been used as a scaffold for the growth in vitro of stem cells in a wide variety of biomaterial engineering studies.

Preparation Note

Prepared with modification of Gallop, P.M.

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1 of 1

This Item	C7661	C1188	C8919
Sigma-Aldrich C5608 Collagen from rabbit skin	Sigma-Aldrich C7661 Collagen from rat tail	Sigma-Aldrich C1188 Collagen from bovine tracheal cartilage	Sigma-Aldrich C8919 Collagen from calf skin
biological source rabbit skin	biological source rat tail	biological source bovine cartilage (tracheal)	biological source bovine (calf) skin
technique(s) cell culture \| stem cell: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) cell culture \| mammalian: suitable
form powder	form powder	form powder	form solution (0.1% solution in 0.1 M acetic acid)
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
Gene Information rabbit ... COL1A2(100008997)	Gene Information rat ... Col1a1(29393)	Gene Information cow ... COL2A1(407142)	Gene Information bovine ... COL1A1(282187), COL2A1(407142)
UniProt accession no. Q28668	UniProt accession no. P02454	UniProt accession no. P02459	UniProt accession no. P02453, P02459

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000447591

0000285025

SLCB8921

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Global Trade Item Number

SKU	GTIN
C5608-100MG	04061833270004

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