83697

Rhodamine 6G

suitable for fluorescence, BioReagent

• Synonym(s): Basic Red 1
• Linear Formula: C₂₈H₃₁N₂O₃Cl
• CAS Number: 989-38-8
• Molecular Weight: 479.01
• EC Number: 213-584-9
• UNSPSC Code: 12171500
• NACRES: NA.32
• PubChem Substance ID: 57652965
• MDL number: MFCD00012665
• Beilstein/REAXYS Number: 3900071

Properties

• product line: BioReagent
• Quality Segment: 200
• form: powder
• solubility: H₂O: soluble, ethanol: soluble
• fluorescence: λ_ex 528 nm; λ_em 551 nm in methanol
• suitability: suitable for fluorescence
• SMILES string: Cl.CCNc1cc2OC3=CC(=N/CC)\C(C)=CC3=C(c2cc1C)c4ccccc4C(=O)OCC
• InChI: 1S/C28H30N2O3.ClH/c1-6-29-23-15-25-21(13-17(23)4)27(19-11-9-10-12-20(19)28(31)32-8-3)22-14-18(5)24(30-7-2)16-26(22)33-25;/h9-16,29H,6-8H2,1-5H3;1H/b30-24+;
• InChI key: VYXSBFYARXAAKO-WTKGSRSZSA-N

Description

Application

Rhodamine 6G has been used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium.[1] It has also been used to label platelets.[2]

Biochem/physiol Actions

A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.

Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays.[3] It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.[4]

Analysis Note

λmax. ∼530 nm, E(1%/1cm) ∼2000-2300 (96% Ethanol)

Safety Information

• pictograms: GHS06,GHS05,GHS09
• signalword: Danger
• hcodes: H301,H317,H318,H410
• pcodes: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves