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54290

Hydroxyethyl-cellulose

viscosity 90-160 cP, 5 % in H2O(25 °C)

Synonym(s):

Cellosize® EP-09

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About This Item

CAS Number:
9004-62-0
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
MFCD00072770
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form

powder

Quality Level

100

color

beige

viscosity

90-160 cP, 5 % in H2O(25 °C)

storage temp.

room temp

SMILES string

O1C(C(C(C(C1CO)OC)O)OCCO)OC2C(OC(C(C2O)O)OC4C(OC(C(C4O)O)C)CO)COC3OC(C(C(C3O)O)OC)CO

InChI

1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

General description

Hydroxyethyl cellulose is a gelling and thickening agent derived from cellulose and is widely used in cosmetics, cleaning solutions and other household products. It is used with hydrophobic drugs in capsule formulations, to improve the drugs dissolution in the gastrointestinal fluids. This process is known as hydrophilization.

Application

Hydroxyethylcellulose is used as a gelling and thickening agent in the development of biostructures for the delivery of hydrophobic drugs. Hydroxyethylcellulose is used in the development of polymer networks and block copolymers useful in separation technology such as capillary electrophoresis and in biofilms and coatings. It is also used for encapsulation of cells in chitosan/glycerophosphate/hydroxyethyl cellulose (chitosan-GP/HEC) gels.[1]

Other Notes

Network-forming polymer in capillary electrophoresis of DNA restriction fragments[2]
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Legal Information

CELLOSIZE is a registered trademark of The Dow Chemical Company or an affiliated company of Dow

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1 of 1

This Item
308633Y0001951434981
Hydroxyethyl-cellulose viscosity 90-160 cP, 5 % in H2O(25 °C)

Sigma-Aldrich

54290

Hydroxyethyl-cellulose

2-Hydroxyethyl cellulose average Mw ~380,000

Sigma-Aldrich

308633

2-Hydroxyethyl cellulose

Hydroxyethyl-cellulose European Pharmacopoeia (EP) Reference Standard

Y0001951

Hydroxyethyl-cellulose

2-Hydroxyethyl cellulose average Mv ~1,300,000

Sigma-Aldrich

434981

2-Hydroxyethyl cellulose

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

-

form

powder

form

powder

form

-

form

powder

storage temp.

room temp

storage temp.

-

storage temp.

2-8°C

storage temp.

-

color

beige

color

-

color

-

color

-

viscosity

90-160 cP, 5 % in H2O(25 °C)

viscosity

-

viscosity

-

viscosity

3,400-5,000 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #4) (30 rpm)(lit.)

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ7171
MKCX1532
MKCT5459
MKCS9500
MKCS6944

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M H Kleemiss et al.
Electrophoresis, 14(5-6), 515-522 (1993-05-01)
Separation of DNA restriction fragments in dilute buffer solutions of network forming polymers such as linear polyacrylamide (PAA), hydroxyethyl cellulose (HEC) and polyvinylalcohol (PVA) in phosphate buffer were investigated. PVA in buffers already became inhomogeneous after a few separations with
Peter Roughley et al.
Biomaterials, 27(3), 388-396 (2005-08-30)
The suitability of chitosan-based hydrogels as scaffolds for the encapsulation of intervertebral disc (IVD) cells and the accumulation of a functional extracellular matrix mimicking that of the nucleus pulposus (NP) was investigated. The specific hypothesis under study was that the
Dan Zhou et al.
Journal of separation science, 34(23), 3441-3450 (2011-11-01)
To stabilize electroosmotic flow (EOF) and suppress protein adsorption onto the silica capillary inner wall, a cationic hydroxyethylcellulose-graft-poly (poly(ethylene glycol) methyl ether methacrylate) (cat-HEC-g-PPEGMA) graft copolymer composed of cationic backbone and bottle brush-like side chains was synthesized for the first
View All Related Papers

Global Trade Item Number

SKUGTIN
54290-100G04061832567310
54290-500G04061832567327

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Hello. What is the molecular weight and viscosity of hydroxyethyl cellulose 5429 and hydroxyethyl cellulose 8.22068?

    1 answer

    1. The molecular weight is undetermined. The viscosity is 80-125 cP.

      Helpful?

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