gas chromatography (GC): suitable, liquid chromatography (LC): suitable
mp
236-239 °C (lit.)
density
0.791 g/cm3 at 20 °C
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
SMILES string
OC(=O)c1cccnc1
InChI
1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI key
PVNIIMVLHYAWGP-UHFFFAOYSA-N
General description
Nicotinic acid, also known as niacin, is a water-soluble vitamin of the B complex and essential human nutrient. Niacin deficiency, often the result of impaired nutritional status associated with conditions ranging from malnutrition to chronic alcoholism, is monitored in patient plasma samples by HPLC. This Certified Spiking Solution® is suitable for use as a starting material in the preparation of linearity standards, calibrators or controls in a variety of testing applications from diagnostic testing of niacin deficiency by HPLC to quality control testing of niacin-based pharmaceutical preparations, dietary supplements, or fortified foods.
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
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Journal of clinical lipidology, 7(2), 178-181 (2013-02-19)
Multiple cholesterol-reducing therapies have been shown to induce the regression of tendon xanthoma in patients with familial hypercholesterolemia. We present 3 cases of adverse reactions in Achilles tendon xanthomas after the addition of niacin and bile acid sequestrants to ongoing
Drugs for hypertriglyceridemia.
The Medical letter on drugs and therapeutics, 55(1411), 17-19 (2013-03-08)
Niacin therapy lives for another day-maybe?
Carl J Lavie et al.
Journal of the American College of Cardiology, 61(21), 2197-2198 (2013-04-02)