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Documentos Principais

PHR1047

Supelco

Fenol

Pharmaceutical Secondary Standard; Certified Reference Material

Sinônimo(s):

Hidroxibenzeno

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About This Item

Fórmula linear:
C6H5OH
Número CAS:
Peso molecular:
94.11
Beilstein:
969616
Número CE:
Número MDL:
Código UNSPSC:
41116107
ID de substância PubChem:
NACRES:
NA.24
Preço e disponibilidade não estão disponíveis no momento.

grau

certified reference material
pharmaceutical secondary standard

Nível de qualidade

Agency

traceable to USP 1524806

densidade de vapor

3.24 (vs air)

pressão de vapor

0.09 psi ( 55 °C)
0.36 mmHg ( 20 °C)

família API

hexylresorcinol, guaiacol, salicylic acid

Certificado de análise (CofA)

current certificate can be downloaded

temperatura de autoignição

1319 °F

Lim. expl.

8.6 %

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

p.e.

182 °C (lit.)

pf

40-42 °C (lit.)

densidade

1.071 g/mL at 25 °C (lit.)

aplicação(ões)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

Formato

neat

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Oc1ccccc1

InChI

1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

chave InChI

ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Procurando produtos similares? Visita Guia de comparação de produtos

Descrição geral

Phenol is a derivative of benzene and is majorly used in the manufacture of bisphenol A, phenolic resins and caprolactam. Its other applications include the manufacture of variety of compounds in pharma industry, dyes, explosives, rubber and agriculture.[1]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Phenol may be used as a standard in determining the concentration of phenol present in samples of water using gas chromatography coupled with electron capture detector (GC-ECD).[2]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC1665 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2

Órgãos-alvo

Nervous system,Kidney,Liver,Skin

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

177.8 °F - closed cup

Ponto de fulgor (°C)

81 °C - closed cup


Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number

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Fenol puriss., ≥99.5% (GC), meets analytical specification of Ph. Eur., BP, USP, crystalline (detached)

Sigma-Aldrich

16016

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Supelco

1.00206

Fenol

Fenol for molecular biology

Sigma-Aldrich

P1037

Fenol

Fenol unstabilized, purified by redistillation, ≥99%

Sigma-Aldrich

328111

Fenol

4-Hydroxyisophthalic acid phyproof® Reference Substance

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Sigma-Aldrich

P5566

Fenol

Encyclopaedia of Occupational Health and Safety: Industries and Occupations, 4 (1998)
Determination of trace amounts of phenol in river waters by gas chromatography
Rennie.JP
Analyst, 107, 327-330 (1982)
Masaharu Nakamura et al.
Bioorganic & medicinal chemistry, 21(7), 1643-1651 (2013-03-07)
We previously reported that bis-phenol derivatives, including LG190178 (3a), possess not only vitamin D receptor (VDR) agonistic activity, but also androgen receptor (AR) antagonistic activity. Here, we describe the design, synthesis and evaluation of silicon-containing bis-phenol derivatives, with the objective
Rita A Busuttil et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(10), 2761-2772 (2014-03-25)
Gene-expression profiling has revolutionized the way we think about cancer and confers the ability to observe the synchronous expression of thousands of genes. The use of putative genome-level expression profiles has allowed biologists to observe the complex interactions of genes
Britta T Eklund et al.
Marine pollution bulletin, 46(2), 171-181 (2003-02-15)
Toxic effects on macroalgae have been compiled. Eighty-two articles have been found in literature during 1959-2000. A total of 120 substances were investigated using 65 different macroalgae species. About one-third of the tested compounds were organic substances (33%), another third

Protocolos

Analytical standard separation of various phenols for research and industrial applications.

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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