850355P

16:0 PC (DPPC)

Avanti Research^™ - A Croda Brand

• Sinônimo(s): 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine; DPPC; PC(16:0/16:0)
• Fórmula empírica (Notação de Hill): C₄₀H₈₀NO₈P
• Número CAS: 63-89-8
• Peso molecular: 734.04
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• descrição: 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
• Ensaio: >99% (TLC)
• forma: powder
• embalagem: pkg of 1 × 1 g (850355P-1g); pkg of 1 × 200 mg (850355P-200mg); pkg of 1 × 25 mg (850355P-25mg); pkg of 1 × 500 mg (850355P-500mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• tipo de lipídio: phospholipids; cardiolipins
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3
• chave InChI: KILNVBDSWZSGLL-UHFFFAOYSA-N

Descrição

Descrição geral

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is synthesized from unsaturated phosphatidylcholine (PC) by direct de novo synthesis via α1,2-dipalmitoyl diacylglycerol intermediate. The enzyme cholinephosphotransferase catalyzes the conversion of 1,2-dipalmitoyl diacylglycerol to DPPC. Synthesis of DPPC also occurs via remodeling pathway involving deacylation of unsaturated PC.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Aplicação

16:0 PC (DPPC) has been used in the generation of thymoquinone (TQ) liposomes, gold nanorods and calcium chloride encapsulated liposomes and bilayers for biophysical studies.

Ações bioquímicas/fisiológicas

1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) is a surfactant and reduces surface tension. It is used in combination with 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) for lipid bilayer generation. DPPC alone and in combination with other phospholipid is effective in drug encapsulation and delivery.

Embalagem

20 mL Clear Glass Screw Cap Vial (850355P-1g)

20 mL Clear Glass Screw Cap Vial (850355P-500mg)

5 mL Amber Glass Screw Cap Vial (850355P-200mg)

5 mL Amber Glass Screw Cap Vial (850355P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable