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Documentos Principais

810255P

Avanti

TopFluor™ Cholesterol

Avanti Research™ - A Croda Brand

Sinônimo(s):

Bodipy Cholesterol; Bdp-Chol

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About This Item

Fórmula empírica (Notação de Hill):
C36H51BF2N2O
Número CAS:
878557-19-8
Peso molecular:
576.61
Número MDL:
MFCD00066515
Código UNSPSC:
12352211
NACRES:
NA.25
Preço e disponibilidade não estão disponíveis no momento.

descrição

23-(dipyrrometheneboron difluoride)-24-norcholesterol

Ensaio

>99% (TLC)

Formulário

powder

embalagem

pkg of 1 × 1 mg (810255P-1mg)
pkg of 1 × 10 mg (810255P-10mg)
pkg of 1 × 5 mg (810255P-5mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

Descrição geral

Biomolecules attached to BODIPY, is readily absorbed in the visible light. It results in greater fluorescence quantum yields. It is highly photostable and less sensitive to change in polarity and pH.[1]

Aplicação

TOPFLUOR™Cholesterol is suitable:
  • for cholesterol-uptake assay[2]
  • for BODIPY cholesterol labeling in live cell experiments[3]
  • for the formation of giant Janus liposomes via poly(vinyl alcohol) (PVA)-assisted lipid swelling [4]

Ações bioquímicas/fisiológicas

BODIPY labelled cholesterol has similar properties to that of the naïve cholesterol.[5] This serves as a cholesterol marker for live cells[1] and aids in trafficking intracellular cholesterol.[5] It might also help in indicating lipid storage diseases.[1]

Embalagem

5 mL Amber Glass Screw Cap Vial (810255P-10mg)
5 mL Amber Glass Screw Cap Vial (810255P-1mg)
5 mL Amber Glass Screw Cap Vial (810255P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

geralmente comprado junto com este produto

Nº do produto
Descrição
Preços

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

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Certificados de análise (COA)

Lot/Batch Number

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Sigma-Aldrich

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Jameson T Crowley et al.
PLoS pathogens, 9(1), e1003109-e1003109 (2013-01-18)
Borrelia burgdorferi, the agent of Lyme disease, has cholesterol and cholesterol-glycolipids that are essential for bacterial fitness, are antigenic, and could be important in mediating interactions with cells of the eukaryotic host. We show that the spirochetes can acquire cholesterol
Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens
Cockburn CL, et al.
Life science alliance, 2(2), e201800292-e201800292 (2019)
Katarina Trajkovic et al.
Science (New York, N.Y.), 319(5867), 1244-1247 (2008-03-01)
Intraluminal vesicles of multivesicular endosomes are either sorted for cargo degradation into lysosomes or secreted as exosomes into the extracellular milieu. The mechanisms underlying the sorting of membrane into the different populations of intraluminal vesicles are unknown. Here, we find
Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure
Solanko LM, et al.
Biophysical Journal, 105(9), 2082-2092 (2013)
James E Shaw et al.
Biophysical journal, 90(6), 2170-2178 (2005-12-20)
Coupling atomic force microscopy (AFM) with high-resolution fluorescence microscopy is an attractive means of identifying membrane domains by both physical topography and fluorescence. We have used this approach to study the ability of a suite of fluorescent molecules to probe
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