840035P

18:1 PS (DOPS)

Avanti Research^™ - A Croda Brand

• Sinônimo(s): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DOPS; PS(18:1(9Z)/18:1(9Z))
• Fórmula empírica (Notação de Hill): C₄₂H₇₇NO₁₀PNa
• Número CAS: 90693-88-2
• Peso molecular: 810.03
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: powder
• embalagem: pkg of 1 × 10 mg (840035P-10mg); pkg of 2 × 100 mg (840035P-200mg); pkg of 5 × 100 mg (840035P-500mg); pkg of 1 × 25 mg (840035P-25mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• solubilidade: soluble (Insoluble in ethanol and DMSO, soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL)
• tipo de lipídio: cardiolipins; phospholipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1
• chave InChI: KPHZNDUWYZIXFY-YORIBCANSA-M

Descrição

Descrição geral

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid,[1] that is found in all polyanionic macromolecules.[2]

Aplicação

18:1 PS (DOPS) has been used:

• in liposomes (multi-lamellar vesicles) preparation[3]
• as a component in incubation buffer to measure exosomes associated procoagulant activity[4]
• in the preparation of lipid vesicles[5]

Ações bioquímicas/fisiológicas

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125).[6] It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.[1]

Embalagem

5 mL Clear Glass Sealed Ampule (840035P-10mg)

5 mL Clear Glass Sealed Ampule (840035P-200mg)

5 mL Clear Glass Sealed Ampule (840035P-25mg)

5 mL Clear Glass Sealed Ampule (840035P-500mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3