900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• Sinônimo(s): Carboxyl sulfonyl fluoride alkyne, Probe building block
• Fórmula empírica (Notação de Hill): C₁₂H₁₃FO₄SSi
• Número CAS: 2088829-06-3
• Peso molecular: 300.38
• Número MDL: MFCD30737995
• Código UNSPSC: 12352106
• NACRES: NA.22

Propriedades

• Ensaio: ≥95%
• forma: solid
• adequação da reação: reagent type: cross-linking reagent
• disponibilidade: available only in USA
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

Descrição

Aplicação

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Outras notas

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informações de segurança

• Pictogramas: GHS02,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H242,H315,H319
• Declarações de precaução: P210 - P235 - P302 + P352 - P305 + P351 + P338 - P370 + P378 - P403
• Classificações de perigo: Eye Irrit. 2 - Self-react. C - Skin Irrit. 2
• Código de classe de armazenamento: 5.2 - Organic peroxides and self-reacting hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable