The Adrenochrome available for sale is only intended for Research Use Only. There have been no clinical studies performed using A5752. There are varied uses for Adrenochrome. The website has a list of some 40 Peer Reviewed Papers for various uses. A quick review of the available abstracts did not reveal papers that were specific for either anti aging or cell revitalization. There would probably be additional reference papers available on the PubMed website.
A5752
Adrenochrome
>95% purity (HPLC), powder
Synonym(s):
3-Hydroxy-1-methyl-5,6-indolinedione
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About This Item
Empirical Formula (Hill Notation):
C9H9NO3
CAS Number:
Molecular Weight:
179.17
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
200-192-8
MDL number:
Pricing and availability is not currently available.
Product Name
Adrenochrome, ≥95% (HPLC)
Quality Segment
assay
≥95% (HPLC)
form
powder
color
red to brown
εmax
3-4.5 at 485-490 nm in water, 9.0-10.5 at 299-304 nm in water
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
CN1CC(O)C2=CC(=O)C(=O)C=C12
InChI
1S/C9H9NO3/c1-10-4-9(13)5-2-7(11)8(12)3-6(5)10/h2-3,9,13H,4H2,1H3
InChI key
RPHLQSHHTJORHI-UHFFFAOYSA-N
Application
Adrenochrome has been used to study the effect of adrenochrome on coronary artery constriction in the rat heart.
Biochem/physiol Actions
Adrenochrome is an oxidation product of adrenaline. It has been implicated in cardiotoxicity. It is a short-lived cytotoxic molecule and is part of the leukocyte response used to kill bacteria. Adrenochrome is also suggested to exhibit psychotomimetic effects. It is used to determine superoxide dismutase activity.
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This Item | |||
|---|---|---|---|
| color red to brown | color - | color pink to very dark red | color - |
| form powder | form powder | form powder | form powder |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
| storage temp. −20°C | storage temp. room temp | storage temp. −20°C | storage temp. −20°C |
| assay ≥95% (HPLC) | assay - | assay ≥95% | assay >99% (TLC) |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Janna Shainsky et al.
Applied and environmental microbiology, 75(14), 4711-4719 (2009-05-26)
Enantiopure sulfoxides are prevalent in drugs and are useful chiral auxiliaries in organic synthesis. The biocatalytic enantioselective oxidation of prochiral sulfides is a direct and economical approach for the synthesis of optically pure sulfoxides. The selection of suitable biocatalysts requires
Viviana S Fluxá et al.
Nature protocols, 3(8), 1270-1277 (2008-08-21)
The adrenaline test for enzymes is a colorimetric enzyme assay based on the quantification of periodate-sensitive reaction products such as 1,2-diols and 1,2-aminoalcohols by back-titration of the oxidant with adrenaline to produce adrenochrome as an easily detectable red product. The
Maria Luisa Genova et al.
Archives of biochemistry and biophysics, 447(2), 167-173 (2006-02-21)
Complex I in bovine heart submitochondrial particles catalyses the NADH-supported generation of superoxide anion; adrenaline is oxidised by superoxide to adrenochrome that, on its hand, is reduced by Complex I, thus establishing a redox cycle that amplifies the superoxide production.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A5752-25MG | 04061832339986 |
| A5752-250MG | 04061832339979 |
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has there been any studies between this and anti aging or cell revitalisation?
1 answer-
Helpful?
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Is this substance synthetic or naturally derived? Some download able Data on this product is dated 1/16/2023. Is this a relatively new substance?
1 answer-
This substance is synthetic organic. The product has been offered previously before 2023. See below for an example of the Certificate of Origin.
https://www.sigmaaldrich.com/coo/undefined/A5752/SHBL7005Helpful?
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