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Glucosamine hydrochloride

Name: Glucosamine hydrochloride
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

D-(+)-Glucosamine hydrochloride, 2-Amino-2-deoxy-D-glucose hydrochloride, Chitosamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₃NO₅ · HCl

CAS Number:

66-84-2

Molecular Weight:

215.63

NACRES:

NA.24

PubChem Substance ID:

329749944

UNSPSC Code:

41116107

Beilstein/REAXYS Number:

4157370

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Properties

grade

pharmaceutical primary standard

API family

glucosamine

manufacturer/tradename

USP

mp

190-194 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1

InChI key

QKPLRMLTKYXDST-NSEZLWDYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glucosamine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Glucosamine and Chondroitin Sulfate Sodium Tablets
Glucosamine and Methylsulfonylmethane Tablets
Glucosamine Hydrochloride
Glucosamine Sulfate Potassium Chloride
Glucosamine Sulfate Sodium Chloride
Glucosamine Tablets
Glucosamine, Chondroitin Sulfate Sodium, and Methylsulfonylmethane Tablets

Biochem/physiol Actions

Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids. D-(+)-Glucosamine inhibits the coaggregation of Candida yeast species with the bacterial strain S. salivarius.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Show Differences

1 of 1

This Item	Y0001406	PHR1199	G1514
USP 1294207 Glucosamine hydrochloride	Y0001406 Glucosamine hydrochloride	Supelco PHR1199 Glucosamine hydrochloride	Sigma-Aldrich G1514 D-(+)-Glucosamine hydrochloride
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename -	manufacturer/tradename -
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade -
format neat	format neat	format neat	format -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) -
mp 190-194 °C (dec.) (lit.)	mp 190-194 °C (dec.) (lit.)	mp 190-194 °C (dec.) (lit.)	mp 190-194 °C (dec.) (lit.)
API family glucosamine	API family glucosamine	API family glucosamine	API family -

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Cruzipain, the major cysteine protease of the pathogenic protozoa Trypanosoma cruzi, is an important virulence factor that plays a key role in the parasite nutrition, differentiation and host cell infection. Cruzipain is synthesized as a zymogen, matured, and delivered to

Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways.

Cuiling Zhong et al.

Nature communications, 11(1), 6330-6330 (2020-12-12)

Endothelial cell (EC) metabolism is thought to be one of the driving forces for angiogenesis. Here we report the identification of the hexosamine D-mannosamine (ManN) as an EC mitogen and survival factor for bovine and human microvascular EC, with an

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Global Trade Item Number

SKU	GTIN
1294207-200MG	04061838726209

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